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4kc1
From Proteopedia
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| - | + | {{STRUCTURE_4kc1| PDB=4kc1 | SCENE= }} | |
| + | ===Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. | ||
| - | + | ==About this Structure== | |
| - | + | [[4kc1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KC1 OCA]. | |
| - | + | [[Category: Homo sapiens]] | |
| + | [[Category: Cuesta-Seijo, J A.]] | ||
| + | [[Category: Lafont, D.]] | ||
| + | [[Category: Palcic, M M.]] | ||
| + | [[Category: Vidal, S.]] | ||
| + | [[Category: Wang, S.]] | ||
| + | [[Category: Adp-gal]] | ||
| + | [[Category: Adp-galnac]] | ||
| + | [[Category: Blood group protein]] | ||
| + | [[Category: Fuc-gal]] | ||
| + | [[Category: Glycosyltransferase]] | ||
| + | [[Category: Gta superfanily]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 05:32, 12 September 2013
Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate
Function
[BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
About this Structure
4kc1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
