4juo
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4juo| PDB=4juo | SCENE= }} | {{STRUCTURE_4juo| PDB=4juo | SCENE= }} | ||
===A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32=== | ===A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32=== | ||
+ | {{ABSTRACT_PUBMED_23965305}} | ||
==Function== | ==Function== | ||
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==Reference== | ==Reference== | ||
- | <references group="xtra"/><references/> | + | <ref group="xtra">PMID:023965305</ref><references group="xtra"/><references/> |
[[Category: Gekko coi]] | [[Category: Gekko coi]] | ||
[[Category: Streptococcus pneumoniae tigr4]] | [[Category: Streptococcus pneumoniae tigr4]] |
Revision as of 09:12, 4 September 2013
Contents |
A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32
Template:ABSTRACT PUBMED 23965305
Function
[PARC_STRPN] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.[1] [2] [PARE_STRPN] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.[3] [4]
About this Structure
4juo is a 6 chain structure with sequence from Gekko coi and Streptococcus pneumoniae tigr4. Full crystallographic information is available from OCA.
Reference
- Laponogov I, Veselkov DA, Crevel IM, Pan XS, Fisher LM, Sanderson MR. Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport. Nucleic Acids Res. 2013 Aug 21. PMID:23965305 doi:10.1093/nar/gkt749
- ↑ Laponogov I, Veselkov DA, Sohi MK, Pan XS, Achari A, Yang C, Ferrara JD, Fisher LM, Sanderson MR. Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target. PLoS ONE. 2007 Mar 21;2(3):e301. PMID:17375187 doi:10.1371/journal.pone.0000301
- ↑ Laponogov I, Pan XS, Veselkov DA, McAuley KE, Fisher LM, Sanderson MR. Structural basis of gate-DNA breakage and resealing by type II topoisomerases. PLoS One. 2010 Jun 28;5(6):e11338. PMID:20596531 doi:10.1371/journal.pone.0011338
- ↑ Laponogov I, Veselkov DA, Sohi MK, Pan XS, Achari A, Yang C, Ferrara JD, Fisher LM, Sanderson MR. Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target. PLoS ONE. 2007 Mar 21;2(3):e301. PMID:17375187 doi:10.1371/journal.pone.0000301
- ↑ Laponogov I, Pan XS, Veselkov DA, McAuley KE, Fisher LM, Sanderson MR. Structural basis of gate-DNA breakage and resealing by type II topoisomerases. PLoS One. 2010 Jun 28;5(6):e11338. PMID:20596531 doi:10.1371/journal.pone.0011338