4by9

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'''Unreleased structure'''
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{{STRUCTURE_4by9| PDB=4by9 | SCENE= }}
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===The structure of the Box CD enzyme reveals regulation of rRNA methylation===
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The entry 4by9 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/FLPA_PYRFU FLPA_PYRFU]] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (By similarity).[HAMAP-Rule:MF_00351] [[http://www.uniprot.org/uniprot/RL7A_PYRFU RL7A_PYRFU]] Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, box H/ACA, box C/D and box C'/D' sRNAs (By similarity).
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Authors: Lapinaite, A., Simon, B., Skjaerven, L., Rakwalska-Bange, M., Gabel, F., Carlomagno, T.
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==About this Structure==
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[[4by9]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BY9 OCA].
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Description: The structure of the Box CD enzyme reveals regulation of rRNA methylation
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[[Category: Pyrococcus furiosus]]
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[[Category: Carlomagno, T.]]
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[[Category: Gabel, F.]]
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[[Category: Lapinaite, A.]]
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[[Category: Rakwalska-Bange, M.]]
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[[Category: Simon, B.]]
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[[Category: Skjaerven, L.]]
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[[Category: Rrna modification]]
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[[Category: Transferase-rna complex]]

Revision as of 06:34, 10 October 2013

Template:STRUCTURE 4by9

The structure of the Box CD enzyme reveals regulation of rRNA methylation

Function

[FLPA_PYRFU] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (By similarity).[HAMAP-Rule:MF_00351] [RL7A_PYRFU] Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, box H/ACA, box C/D and box C'/D' sRNAs (By similarity).

About this Structure

4by9 is a 18 chain structure with sequence from Pyrococcus furiosus. Full experimental information is available from OCA.

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OCA

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