4mhv

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m (Protected "4mhv" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4mhv| PDB=4mhv | SCENE= }}
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===Crystal structure of the PNT domain of human ETS2===
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The entry 4mhv is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/ETS2_HUMAN ETS2_HUMAN]] Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.<ref>PMID:11909962</ref>
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Authors: Newman, J.A., Cooper, C.D.O., Krojer, T., Shrestha, L., Burgess-brown, N., Arrowsmith, C.H., Bountra, C., Edwards, A., Gileadi, O.
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==About this Structure==
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[[4mhv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHV OCA].
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Description: Crystal structure of the PNT domain of human ETS2
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Bountra, C.]]
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[[Category: Burgess-brown, N.]]
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[[Category: Cooper, C D.O.]]
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[[Category: Edwards, A.]]
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[[Category: Gileadi, O.]]
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[[Category: Krojer, T.]]
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[[Category: Newman, J A.]]
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[[Category: Shrestha, L.]]
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[[Category: Transcription]]
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[[Category: Transcription factor]]

Revision as of 08:22, 29 September 2013

Template:STRUCTURE 4mhv

Contents

Crystal structure of the PNT domain of human ETS2

Function

[ETS2_HUMAN] Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.[1]

About this Structure

4mhv is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. ↑ Wasylyk C, Schlumberger SE, Criqui-Filipe P, Wasylyk B. Sp100 interacts with ETS-1 and stimulates its transcriptional activity. Mol Cell Biol. 2002 Apr;22(8):2687-702. PMID:11909962

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OCA

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