1w33

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 8: Line 8:
==About this Structure==
==About this Structure==
-
1W33 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Borrelia_burgdorferi Borrelia burgdorferi]] with GOL as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W33 OCA]].
+
1W33 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Borrelia_burgdorferi Borrelia burgdorferi] with GOL as [http://en.wikipedia.org/wiki/ligand ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W33 OCA].
==Reference==
==Reference==
Line 33: Line 33:
[[Category: tick]]
[[Category: tick]]
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 16:23:26 2007''
+
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 5 13:26:24 2007''

Revision as of 11:21, 5 November 2007

Image:1w33.gif

1w33, resolution 2.7Å

Drag the structure with the mouse to rotate

BBCRASP-1 FROM BORRELIA BURGDORFERI

Overview

Borrelia burgdorferi, a spirochete transmitted to human hosts during, feeding of infected Ixodes ticks, is the causative agent of Lyme disease., Serum-resistant B. burgdorferi strains cause a chronic, multisystemic form, of the disease and bind complement factor H (FH) and FH-like protein 1, (FHL-1) on the spirochete surface. Here we report the atomic structure for, the key FHL-1- and FH-binding protein BbCRASP-1 and reveal a homodimer, that presents a novel target for drug design.

About this Structure

1W33 is a Single protein structure of sequence from Borrelia burgdorferi with GOL as ligand. Structure known Active Site: AC1. Full crystallographic information is available from OCA.

Reference

A novel fold for the factor H-binding protein BbCRASP-1 of Borrelia burgdorferi., Cordes FS, Roversi P, Kraiczy P, Simon MM, Brade V, Jahraus O, Wallis R, Skerka C, Zipfel PF, Wallich R, Lea SM, Nat Struct Mol Biol. 2005 Mar;12(3):276-7. Epub 2005 Feb 13. PMID:15711564

Page seeded by OCA on Mon Nov 5 13:26:24 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1w33"
Personal tools