2o23

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[[Image:2o23.jpg|left|200px]]<br /><applet load="2o23" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2o23.jpg|left|200px]]
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caption="2o23, resolution 1.20&Aring;" />
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'''The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A'''<br />
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{{Structure
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|PDB= 2o23 |SIZE=350|CAPTION= <scene name='initialview01'>2o23</scene>, resolution 1.20&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/3-hydroxy-2-methylbutyryl-CoA_dehydrogenase 3-hydroxy-2-methylbutyryl-CoA dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.178 1.1.1.178]
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|GENE= HADH2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2O23 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAD:'>NAD</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3-hydroxy-2-methylbutyryl-CoA_dehydrogenase 3-hydroxy-2-methylbutyryl-CoA dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.178 1.1.1.178] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O23 OCA].
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2O23 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O23 OCA].
[[Category: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase]]
[[Category: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: schad]]
[[Category: schad]]
[[Category: sgc]]
[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
[[Category: type ii hadh]]
[[Category: type ii hadh]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:13:44 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:54:06 2008''

Revision as of 15:54, 20 March 2008

Image:2o23.jpg


PDB ID 2o23

Drag the structure with the mouse to rotate
, resolution 1.20Å
Ligands: and
Gene: HADH2 (Homo sapiens)
Activity: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, with EC number 1.1.1.178
Coordinates: save as pdb, mmCIF, xml



The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A


Disease

Known disease associated with this structure: 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency OMIM:[300256]

About this Structure

2O23 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 17:54:06 2008

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OCA

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