4c2s
From Proteopedia
(Difference between revisions)
| Line 10: | Line 10: | ||
[[Category: Henriksen, A.]] | [[Category: Henriksen, A.]] | ||
[[Category: Palcic, M.]] | [[Category: Palcic, M.]] | ||
| - | [[Category: | + | [[Category: Weadge, J T.]] |
[[Category: Abo]] | [[Category: Abo]] | ||
[[Category: Blood group antigen]] | [[Category: Blood group antigen]] | ||
Revision as of 06:44, 16 October 2013
Crystal structure of the fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA P156L mutant) in complex with UDP and deoxy-H-antigen acceptor
Function
[BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
About this Structure
4c2s is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
