4h5t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4h5t| PDB=4h5t | SCENE= }}
 +
===HSC70 NBD with ADP and Mg===
-
The entry 4h5t is ON HOLD until Mar 18 2015
+
==Function==
 +
[[http://www.uniprot.org/uniprot/HSP7C_HUMAN HSP7C_HUMAN]] Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.<ref>PMID:10722728</ref>
-
Authors: Stec, B.
+
==About this Structure==
 +
[[4h5t]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H5T OCA].
-
Description: HSC70 NBD with ADP and Mg
+
==Reference==
 +
<references group="xtra"/><references/>
 +
[[Category: Stec, B.]]
 +
[[Category: Hsc70 nbd]]
 +
[[Category: Transcription]]

Revision as of 09:29, 19 March 2014

Template:STRUCTURE 4h5t

Contents

HSC70 NBD with ADP and Mg

Function

[HSP7C_HUMAN] Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.[1]

About this Structure

4h5t is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Yahata T, de Caestecker MP, Lechleider RJ, Andriole S, Roberts AB, Isselbacher KJ, Shioda T. The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors. J Biol Chem. 2000 Mar 24;275(12):8825-34. PMID:10722728

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4h5t"
Personal tools