3wdc
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_3wdc| PDB=3wdc | SCENE= }} | {{STRUCTURE_3wdc| PDB=3wdc | SCENE= }} | ||
===N-terminal domain of Mycobacterium tuberculosis ClpC1 bound to Cyclomarin A=== | ===N-terminal domain of Mycobacterium tuberculosis ClpC1 bound to Cyclomarin A=== | ||
| + | {{ABSTRACT_PUBMED_24022489}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
| - | [[3wdc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3wdc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884] and [http://en.wikipedia.org/wiki/Chainia_sp. Chainia sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WDC OCA]. |
| - | + | ||
| - | [[Category: | + | ==Reference== |
| + | <ref group="xtra">PMID:024022489</ref><references group="xtra"/><references/> | ||
| + | [[Category: Chainia sp.]] | ||
[[Category: Noble, C G.]] | [[Category: Noble, C G.]] | ||
[[Category: Vasudevan, D.]] | [[Category: Vasudevan, D.]] | ||
[[Category: Chaperone]] | [[Category: Chaperone]] | ||
[[Category: Chaperone-antimicrobial protein complex]] | [[Category: Chaperone-antimicrobial protein complex]] | ||
Revision as of 12:25, 11 December 2013
Contents |
N-terminal domain of Mycobacterium tuberculosis ClpC1 bound to Cyclomarin A
Template:ABSTRACT PUBMED 24022489
Function
[CLPC1_MYCTU] ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity). Degrades anti-sigma-E factor RseA in the presence of ClpP2.
About this Structure
3wdc is a 2 chain structure with sequence from "bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884 and Chainia sp.. Full crystallographic information is available from OCA.
Reference
- Vasudevan D, Rao SP, Noble CG. Structural basis of mycobacterial inhibition by cyclomarin A. J Biol Chem. 2013 Oct 25;288(43):30883-91. doi: 10.1074/jbc.M113.493767. Epub, 2013 Sep 10. PMID:24022489 doi:http://dx.doi.org/10.1074/jbc.M113.493767
