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4lp0

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'''Unreleased structure'''
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{{STRUCTURE_4lp0| PDB=4lp0 | SCENE= }}
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===Crystal structure of a topoisomerase ATP inhibitor===
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{{ABSTRACT_PUBMED_24098982}}
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The entry 4lp0 is ON HOLD until sometime in the future
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==About this Structure==
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[[4lp0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LP0 OCA].
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Authors: Basarab, G.S., Manchester, J.I., Bist, S., Boriack-Sjodin, P.A., Dangel, B., Illingsworth, R., Uria-Nickelsen, M., Sherer, B.A., Sriram, S., Eakin, A.E.
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==Reference==
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<ref group="xtra">PMID:024098982</ref><references group="xtra"/><references/>
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Description: Crystal structure of a topoisomerase ATP inhibitor
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[[Category: Basarab, G S.]]
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[[Category: Bist, S.]]
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[[Category: Boriack-Sjodin, P A.]]
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[[Category: Dangel, B.]]
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[[Category: Eakin, A E.]]
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[[Category: Illingsworth, R.]]
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[[Category: Manchester, J I.]]
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[[Category: Sherer, B A.]]
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[[Category: Sriram, S.]]
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[[Category: Uria-Nickelsen, M.]]
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[[Category: Antimicrobial]]
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[[Category: Atp binding]]
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[[Category: Atpase domain]]
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[[Category: Isomerase-isomerase inhibitor complex]]
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[[Category: Protein-inhibitor complex]]
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[[Category: Structure-based drug design]]
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[[Category: Virtual screen]]

Revision as of 08:19, 13 November 2013

Template:STRUCTURE 4lp0

Crystal structure of a topoisomerase ATP inhibitor

Template:ABSTRACT PUBMED 24098982

About this Structure

4lp0 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Basarab GS, Manchester JI, Bist S, Boriack-Sjodin PA, Dangel B, Illingworth R, Sherer BA, Sriram S, Uria-Nickelsen M, Eakin AE. Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents. J Med Chem. 2013 Oct 29. PMID:24098982 doi:http://dx.doi.org/10.1021/jm401208b

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OCA

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