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4irq
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of catalytic domain of human beta1,4galactosyltransferase 7 in closed conformation in complex with manganese and UDP== | |
| - | + | <StructureSection load='4irq' size='340' side='right' caption='[[4irq]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | ==Disease== | + | <table><tr><td colspan='2'>[[4irq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IRQ FirstGlance]. <br> |
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4irp|4irp]], [[3lw6|3lw6]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">4galactosyltransferase, B4GALT7, beta1, UNQ748/PRO1478, XGALT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4irq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4irq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4irq RCSB], [http://www.ebi.ac.uk/pdbsum/4irq PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
[[http://www.uniprot.org/uniprot/B4GT7_HUMAN B4GT7_HUMAN]] Ehlers-Danlos syndrome, progeroid type. The disease is caused by mutations affecting the gene represented in this entry. | [[http://www.uniprot.org/uniprot/B4GT7_HUMAN B4GT7_HUMAN]] Ehlers-Danlos syndrome, progeroid type. The disease is caused by mutations affecting the gene represented in this entry. | ||
| - | + | == Function == | |
| - | ==Function== | + | |
[[http://www.uniprot.org/uniprot/B4GT7_HUMAN B4GT7_HUMAN]] Required for the biosynthesis of the tetrasaccharide linkage region of proteoglycans, especially for small proteoglycans in skin fibroblasts. | [[http://www.uniprot.org/uniprot/B4GT7_HUMAN B4GT7_HUMAN]] Required for the biosynthesis of the tetrasaccharide linkage region of proteoglycans, especially for small proteoglycans in skin fibroblasts. | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Qasba, P K | + | [[Category: Qasba, P K]] |
| - | [[Category: Ramakrishnan, B | + | [[Category: Ramakrishnan, B]] |
| - | [[Category: Tsutsui, Y | + | [[Category: Tsutsui, Y]] |
[[Category: Closed conformation]] | [[Category: Closed conformation]] | ||
[[Category: Glycosyltransferase]] | [[Category: Glycosyltransferase]] | ||
Revision as of 14:27, 4 January 2015
Crystal structure of catalytic domain of human beta1,4galactosyltransferase 7 in closed conformation in complex with manganese and UDP
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