4kgo
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4kgo| PDB=4kgo | SCENE= }} | {{STRUCTURE_4kgo| PDB=4kgo | SCENE= }} | ||
===Crystal Structure of double Leucine to Methionine mutant human splunc-1 lacking the secretion signal sequence=== | ===Crystal Structure of double Leucine to Methionine mutant human splunc-1 lacking the secretion signal sequence=== | ||
| + | {{ABSTRACT_PUBMED_24043776}} | ||
==Function== | ==Function== | ||
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==Reference== | ==Reference== | ||
| - | <references group="xtra"/><references/> | + | <ref group="xtra">PMID:024043776</ref><references group="xtra"/><references/> |
[[Category: Rhizobium loessense]] | [[Category: Rhizobium loessense]] | ||
[[Category: Betts, L.]] | [[Category: Betts, L.]] | ||
Revision as of 05:10, 10 October 2013
Contents |
Crystal Structure of double Leucine to Methionine mutant human splunc-1 lacking the secretion signal sequence
Template:ABSTRACT PUBMED 24043776
Function
[BPIA1_HUMAN] May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways.[1]
About this Structure
4kgo is a 2 chain structure with sequence from Rhizobium loessense. Full crystallographic information is available from OCA.
Reference
- Garland AL, Walton WG, Coakley RD, Tan CD, Gilmore RC, Hobbs CA, Tripathy A, Clunes LA, Bencharit S, Stutts MJ, Betts L, Redinbo MR, Tarran R. Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):15973-15978. Epub 2013 Sep 16. PMID:24043776 doi:http://dx.doi.org/10.1073/pnas.1311999110
- ↑ Lindahl M, Stahlbom B, Tagesson C. Identification of a new potential airway irritation marker, palate lung nasal epithelial clone protein, in human nasal lavage fluid with two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-time of flight. Electrophoresis. 2001 May;22(9):1795-800. PMID:11425234 doi:<1795::AID-ELPS1795>3.0.CO;2-J 10.1002/1522-2683(200105)22:9<1795::AID-ELPS1795>3.0.CO;2-J
