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4mxi

From Proteopedia

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m (Protected "4mxi" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4mxi| PDB=4mxi | SCENE= }}
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===ClpP Ser98dhA===
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{{ABSTRACT_PUBMED_24106749}}
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The entry 4mxi is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/CLPP_STAA8 CLPP_STAA8]] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity).
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Authors: Gersch, M., Kolb, R., Alte, F., Groll, M., Sieber, S.A.
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==About this Structure==
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[[4mxi]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Xenopus_itombwensis Xenopus itombwensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MXI OCA].
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Description: ClpP Ser98dhA
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==Reference==
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<ref group="xtra">PMID:024106749</ref><references group="xtra"/><references/>
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[[Category: Endopeptidase Clp]]
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[[Category: Xenopus itombwensis]]
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[[Category: Alte, F.]]
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[[Category: Gersch, M.]]
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[[Category: Groll, M.]]
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[[Category: Kolb, R.]]
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[[Category: Sieber, S A.]]
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[[Category: Clpp]]
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[[Category: Complex disassembly]]
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[[Category: Dehydroalanine]]
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[[Category: Hydrolase]]
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[[Category: Inhibition]]
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[[Category: Serine protease]]

Revision as of 06:46, 23 October 2013

Template:STRUCTURE 4mxi

Contents

ClpP Ser98dhA

Template:ABSTRACT PUBMED 24106749

Function

[CLPP_STAA8] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity).

About this Structure

4mxi is a 7 chain structure with sequence from Xenopus itombwensis. Full crystallographic information is available from OCA.

Reference

  • Gersch M, Kolb R, Alte F, Groll M, Sieber SA. Disruption of oligomerization and dehydroalanine formation as mechanisms for ClpP protease inhibition. J Am Chem Soc. 2013 Oct 9. PMID:24106749 doi:http://dx.doi.org/10.1021/ja4082793

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OCA

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