4lku
From Proteopedia
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| - | + | ==Structure of the C-terminal domain of the E. coli mechanosensitive channel of large conductance== | |
| - | + | <StructureSection load='4lku' size='340' side='right' caption='[[4lku]], [[Resolution|resolution]] 1.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[4lku]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LKU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LKU FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lku OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lku RCSB], [http://www.ebi.ac.uk/pdbsum/4lku PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of the cytoplasmic domain (CTD) from the mechanosensitive channel of large conductance (MscL) in E. coli has been determined at 1.45 A resolution. This domain forms a pentameric coiled coil similar to that observed in the structure of MscL from M. tuberculosis and also found in the Cartilage Oligomeric Matrix Protein (COMPcc). It contains canonical hydrophobic and atypical ionic interactions compared to previously characterized coiled coil structures. Thermodynamic analysis indicates that while the free EcMscL-CTD is less stable than other coiled coils, it is likely to remain folded in context of the full-length channel. | ||
| - | + | Structure and stability of the C-terminal helical bundle of the E. coli mechanosensitive channel of large conductance.,Walton TA, Rees DC Protein Sci. 2013 Aug 29. doi: 10.1002/pro.2360. PMID:24038743<ref>PMID:24038743</ref> | |
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| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| - | [[Category: Rees, D C | + | </StructureSection> |
| - | [[Category: Walton, T A | + | [[Category: Rees, D C]] |
| + | [[Category: Walton, T A]] | ||
[[Category: Pentamer]] | [[Category: Pentamer]] | ||
[[Category: Transport protein]] | [[Category: Transport protein]] | ||
Revision as of 14:47, 21 December 2014
Structure of the C-terminal domain of the E. coli mechanosensitive channel of large conductance
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