Peroxiredoxin

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Line 57: Line 57:
[[2rii]], [[3hy2]] – hPrx 1 (mutant)+sulfiredoxin 1<br />
[[2rii]], [[3hy2]] – hPrx 1 (mutant)+sulfiredoxin 1<br />
[[2z9s]] – Prx 1 (mutant) - rat<br />
[[2z9s]] – Prx 1 (mutant) - rat<br />
-
[[4kw6]], [[4fh8]] – Prx 1 – Ancylostoma ceylanicum<br />
+
[[4kw6]], [[4fh8]] – Prx 1 – ''Ancylostoma ceylanicum''<br />
===Peroxiredoxin 2===
===Peroxiredoxin 2===

Revision as of 09:19, 9 October 2013

Image:1qq2.png
Crystal Structure of Peroxiredoxin (1qq2)

Template:STRUCTURE 1qq2











Peroxiredoxin (Prx) is an antioxidant enzyme. In the Prxs the active-site Cys is oxidized to sulfenic acid byperoxide. The Prxs are divided into typical 2-Cys Prx, atypical 2-Cys Prx and 1-Cys Prx. Prx 5 is expressed in mammalian tissue. The images at the left and at the right correspond to one representative Prx, i.e. the crystal structure of Peroxiredoxin from rat (1qq2).

Contents








3D Structures of Peroxiredoxin

Updated on 09-October-2013

1qq2 – 2Cys-Prx – rat
2c0d – Pf2Cys-Prx – Plasmodium falciparum
1xiy – Pf1Cys-Prx
1xcc, 2h01, 3tb2 - 1Cys-Prx – Plasmodium yoelii
2i81 - 2Cys-Prx – Plasmodium vivax
1qmv - h2Cys-Prx – human
2a4v – yPrx dot5 C-terminal (mutant) – yeast
3cmi – yPrx hyr1
4g2e – Prx – Sulfolobus tokodaii
3sbc – yPrx Tsa1 (mutant)
1uul - 2Cys-Prx – Trypanosoma cruzi
1we0 – Prx – Amphibacillus xylanus
2cv4, 2cx3, 2cx4 – Prx – Aeropyrum pernix
3drn – SsPrx – Sulfolobus solfataricus
3hjp – SsPrx (mutant)
3ixr – Prx PRXQ (mutant) – Xylella fastidiosa

Peroxiredoxin 1

2rii, 3hy2 – hPrx 1 (mutant)+sulfiredoxin 1
2z9s – Prx 1 (mutant) - rat
4kw6, 4fh8 – Prx 1 – Ancylostoma ceylanicum

Peroxiredoxin 2

1tp9 – Prx II – Populus trichocarpa
2pwj – Prx II – garden pea
4dsq, 4dsr, 4h86 – yPrx II
4dss – yPrx II (mutant) + thioredoxin II

Peroxiredoxin 3

1zye – Prx III (mutant) – bovine

Peroxiredoxin 4

3tjf, 3tjg, 3tjj, 3tjk, 3tkr - hPrx 4 (mutant)
3qpm – Prx 4 – Larimichtys crocea
2pn8, 3tjb, 3tkp, 3tkq, 3tks – hPrx 4

Peroxiredoxin 5

1urm – hPrx 5 (mutant) – human
2vl2, 2vl3, 2vl9, 1h4o, 1hd2, 1oc3 – hPrx 5
3mng – hPrx 5+DTT
2wfc – lPrx 5 - lugworm
2xhf – Prx 5 – Alvinella pompejana

Peroxiredoxin 6

2v2g – lPrx 6
2v32, 2v41 – lPrx 6 (mutant)

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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