2owl

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[[Image:2owl.gif|left|200px]]<br /><applet load="2owl" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2owl.gif|left|200px]]
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caption="2owl, resolution 2.40&Aring;" />
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'''Crystal structure of E. coli RdgC'''<br />
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{{Structure
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|PDB= 2owl |SIZE=350|CAPTION= <scene name='initialview01'>2owl</scene>, resolution 2.40&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
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|ACTIVITY=
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|GENE= rdgC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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}}
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'''Crystal structure of E. coli RdgC'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2OWL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OWL OCA].
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2OWL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OWL OCA].
==Reference==
==Reference==
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Ring structure of the Escherichia coli DNA-binding protein RdgC associated with recombination and replication fork repair., Briggs GS, McEwan PA, Yu J, Moore T, Emsley J, Lloyd RG, J Biol Chem. 2007 Apr 27;282(17):12353-7. Epub 2007 Feb 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17308310 17308310]
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Ring structure of the Escherichia coli DNA-binding protein RdgC associated with recombination and replication fork repair., Briggs GS, McEwan PA, Yu J, Moore T, Emsley J, Lloyd RG, J Biol Chem. 2007 Apr 27;282(17):12353-7. Epub 2007 Feb 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17308310 17308310]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: replication]]
[[Category: replication]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:23:26 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:05:28 2008''

Revision as of 16:05, 20 March 2008

Image:2owl.gif


PDB ID 2owl

Drag the structure with the mouse to rotate
, resolution 2.40Å
Ligands:
Gene: rdgC (Escherichia coli)
Coordinates: save as pdb, mmCIF, xml



Crystal structure of E. coli RdgC


Overview

The DNA-binding protein, RdgC, is associated with recombination and replication fork repair in Escherichia coli and with the virulence-associated, pilin antigenic variation mediated by RecA and other recombination proteins in Neisseria species. We solved the structure of the E. coli protein and refined it to 2.4A. RdgC crystallizes as a dimer with a head-to-head, tail-to-tail organization forming a ring with a 30 A diameter hole at the center. The protein fold is unique and reminiscent of a horseshoe with twin gates closing the open end. The central hole is lined with positively charged residues and provides a highly plausible DNA binding channel consistent with the nonspecific mode of binding detected in vitro and with the ability of RdgC to modulate RecA function in vivo.

About this Structure

2OWL is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Ring structure of the Escherichia coli DNA-binding protein RdgC associated with recombination and replication fork repair., Briggs GS, McEwan PA, Yu J, Moore T, Emsley J, Lloyd RG, J Biol Chem. 2007 Apr 27;282(17):12353-7. Epub 2007 Feb 16. PMID:17308310

Page seeded by OCA on Thu Mar 20 18:05:28 2008

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