4mz8

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'''Unreleased structure'''
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==Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with an Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound C91==
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<StructureSection load='4mz8' size='340' side='right' caption='[[4mz8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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The entry 4mz8 is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4mz8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MZ8 FirstGlance]. <br>
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Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Anderson, W.F., Joachimiak, A., Csgid, Center for Structural Genomics of Infectious Diseases (CSGID)
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2F2:DIMETHYL+ETHER'>2F2</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=C91:N-(NAPHTHALEN-2-YL)-2-[2-(PYRIDIN-2-YL)-1H-BENZIMIDAZOL-1-YL]ACETAMIDE'>C91</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mz1|4mz1]]</td></tr>
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Description: Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound C91
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mz8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mz8 RCSB], [http://www.ebi.ac.uk/pdbsum/4mz8 PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: IMP dehydrogenase]]
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[[Category: Anderson, W F.]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Csgid]]
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[[Category: Gu, M.]]
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[[Category: Joachimiak, A.]]
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[[Category: Kim, Y.]]
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[[Category: Makowska-Grzyska, M.]]
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[[Category: Alpha-beta structure]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Niaid]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Structural genomic]]
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[[Category: Tim barrel]]

Revision as of 10:28, 16 July 2014

Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with an Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound C91

4mz8, resolution 2.50Å

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