Sandbox Reserved 784
From Proteopedia
(Difference between revisions)
(→Structure) |
(→Structure) |
||
Line 10: | Line 10: | ||
==Structure== | ==Structure== | ||
- | + | Pyruvate kinase is a <scene name='56/563196/Overall_structure_final/1'>homotetramer</scene>, meaning it has four identical <scene name='56/563196/Chain_a/3'>chains</scene>. | |
- | + | This enzyme contains both <scene name='56/563196/Alpha/1'>alpha helices</scene> and <scene name='56/563196/Beta/1'>beta sheets</scene>. It has three <scene name='56/563196/Domains/2'>domains</scene>. <scene name='56/563196/Domains_1/1'>Domain 1</scene> consists of an alpha-beta-alpha 3-layer sandwich. <scene name='56/563196/Domains_2/1'>Domain 2</scene> consists of a parallel alpha-beta barrel. <scene name='56/563196/Domains_3/1'>Domain 3</scene> consists of an anti-parallel beta-barrel. | |
- | + | ||
Hydrogen bonds and disulfide bonds | Hydrogen bonds and disulfide bonds | ||
Line 20: | Line 19: | ||
Solvent | Solvent | ||
- | The ligands, substrate, | + | The ligands, substrate, cofactors, etc |
Ligand contacts | Ligand contacts | ||
catalytic residues | catalytic residues |
Revision as of 01:10, 18 October 2013
This Sandbox is Reserved from Oct 10, 2013, through May 20, 2014 for use in the course "CHEM 410 Biochemistry 1 and 2" taught by Hanna Tims at the Messiah College. This reservation includes Sandbox Reserved 780 through Sandbox Reserved 807. |
To get started:
More help: Help:Editing |
|
Introduction
Pyruvate kinase (aka transferase, PDB 4IP7) What's it do Research about it
Structure
Pyruvate kinase is a , meaning it has four identical . This enzyme contains both and . It has three . consists of an alpha-beta-alpha 3-layer sandwich. consists of a parallel alpha-beta barrel. consists of an anti-parallel beta-barrel.
Hydrogen bonds and disulfide bonds
Hydrophobic and hydrophilic residues
Solvent
The ligands, substrate, cofactors, etc
Ligand contacts
catalytic residues