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4mxi

From Proteopedia

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==About this Structure==
==About this Structure==
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[[4mxi]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Xenopus_itombwensis Xenopus itombwensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MXI OCA].
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[[4mxi]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Staa8 Staa8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MXI OCA].
==Reference==
==Reference==
<ref group="xtra">PMID:024106749</ref><references group="xtra"/><references/>
<ref group="xtra">PMID:024106749</ref><references group="xtra"/><references/>
[[Category: Endopeptidase Clp]]
[[Category: Endopeptidase Clp]]
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[[Category: Xenopus itombwensis]]
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[[Category: Staa8]]
[[Category: Alte, F.]]
[[Category: Alte, F.]]
[[Category: Gersch, M.]]
[[Category: Gersch, M.]]

Revision as of 04:34, 13 February 2014

Template:STRUCTURE 4mxi

Contents

ClpP Ser98dhA

Template:ABSTRACT PUBMED 24106749

Function

[CLPP_STAA8] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity).

About this Structure

4mxi is a 7 chain structure with sequence from Staa8. Full crystallographic information is available from OCA.

Reference

  • Gersch M, Kolb R, Alte F, Groll M, Sieber SA. Disruption of oligomerization and dehydroalanine formation as mechanisms for ClpP protease inhibition. J Am Chem Soc. 2013 Oct 9. PMID:24106749 doi:http://dx.doi.org/10.1021/ja4082793

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OCA

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