3whc

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'''Unreleased structure'''
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{{STRUCTURE_3whc| PDB=3whc | SCENE= }}
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===Crystal structure of a transcriptional regulator FadR from Bacillus subtilis in complex with stearoyl-CoA===
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{{ABSTRACT_PUBMED_24356978}}
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The entry 3whc is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/FADR_BACSU FADR_BACSU]] Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length.
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Authors: Fujihashi, M., Nakatani, T., Miki, K.
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==About this Structure==
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[[3whc]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WHC OCA].
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Description: Crystal structure of a transcriptional regulator FadR from Bacillus subtilis in complex with stearoyl-CoA
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==Reference==
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<ref group="xtra">PMID:024356978</ref><references group="xtra"/><references/>
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[[Category: Fujihashi, M.]]
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[[Category: Miki, K.]]
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[[Category: Nakatani, T.]]
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[[Category: Fatty acid degradation]]
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[[Category: Transcription]]
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[[Category: Transcriptional regulator]]

Revision as of 08:58, 19 March 2014

Template:STRUCTURE 3whc

Contents

Crystal structure of a transcriptional regulator FadR from Bacillus subtilis in complex with stearoyl-CoA

Template:ABSTRACT PUBMED 24356978

Function

[FADR_BACSU] Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length.

About this Structure

3whc is a 6 chain structure. Full crystallographic information is available from OCA.

Reference

  • Fujihashi M, Nakatani T, Hirooka K, Matsuoka H, Fujita Y, Miki K. Structural characterization of a ligand-bound form of Bacillus subtilis FadR involved in the regulation of fatty acid degradation. Proteins. 2013 Dec 20. doi: 10.1002/prot.24496. PMID:24356978 doi:http://dx.doi.org/10.1002/prot.24496

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OCA

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