4lk0
From Proteopedia
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{{STRUCTURE_4lk0| PDB=4lk0 | SCENE= }} | {{STRUCTURE_4lk0| PDB=4lk0 | SCENE= }} | ||
===Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex=== | ===Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex=== | ||
| + | {{ABSTRACT_PUBMED_24218560}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
| - | [[4lk0]] is a 14 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LK0 OCA]. | + | [[4lk0]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt7 Bpt7], [http://en.wikipedia.org/wiki/Ecobw Ecobw], [http://en.wikipedia.org/wiki/Ecod1 Ecod1] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LK0 OCA]. |
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:024218560</ref><references group="xtra"/><references/> | ||
| + | [[Category: Bpt7]] | ||
[[Category: DNA-directed RNA polymerase]] | [[Category: DNA-directed RNA polymerase]] | ||
| + | [[Category: Ecobw]] | ||
| + | [[Category: Ecod1]] | ||
| + | [[Category: Ecoli]] | ||
[[Category: Bae, B.]] | [[Category: Bae, B.]] | ||
[[Category: Darst, S A.]] | [[Category: Darst, S A.]] | ||
[[Category: Dna directed rna polymerase]] | [[Category: Dna directed rna polymerase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 06:15, 4 December 2013
Contents |
Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex
Template:ABSTRACT PUBMED 24218560
Function
[VRPI_BPT7] Bacterial RNA polymerase inhibitor, which is expressed in the late stage of lytic development, is also essential for continuous synthesis of phage DNA and functions in the packaging of the viral genome into the mature phage particle. [C9QUL2_ECOD1] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).[HAMAP-Rule:MF_00366][SAAS:SAAS012293_004_017283] [C9QXI7_ECOD1] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[HAMAP-Rule:MF_00059] [C5A0S8_ECOBW] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[SAAS:SAAS012754_004_011999] [C9QV90_ECOD1] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[HAMAP-Rule:MF_01321][RuleBase:RU000432] [RPOD_ECOLI] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium.
About this Structure
4lk0 is a 14 chain structure with sequence from Bpt7, Ecobw, Ecod1 and Ecoli. Full crystallographic information is available from OCA.
Reference
- Bae B, Davis E, Brown D, Campbell EA, Wigneshweraraj S, Darst SA. Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma70 domain 1.1. Proc Natl Acad Sci U S A. 2013 Nov 11. PMID:24218560 doi:http://dx.doi.org/10.1073/pnas.1314576110
