2rtx

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'''Unreleased structure'''
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{{STRUCTURE_2rtx| PDB=2rtx | SCENE= }}
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===Solution structure of the GGQ domain of YaeJ protein from Escherichia coli===
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{{ABSTRACT_PUBMED_24322300}}
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The entry 2rtx is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/ARFB_ECOLI ARFB_ECOLI]] Rescues stalled ribosomes. Can hydrolyze peptidyl-tRNA on ribosomes stalled by both non-stop mRNAs and mRNAs that contain rare codon clusters. May function as a complementary rescue system when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system or the alternative ribosome-rescue factor A.<ref>PMID:21418110</ref> <ref>PMID:21051357</ref>
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Authors: Nameki, N., Enomoto, M., Kogure, H., Tochio, N., Guntert, P.
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==About this Structure==
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[[2rtx]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RTX OCA].
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Description: Solution structure of the GGQ domain of YaeJ protein from Escherichia coli
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==Reference==
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<ref group="xtra">PMID:024322300</ref><references group="xtra"/><references/>
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[[Category: Aminoacyl-tRNA hydrolase]]
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[[Category: Enomoto, M.]]
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[[Category: Guntert, P.]]
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[[Category: Kogure, H.]]
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[[Category: Nameki, N.]]
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[[Category: Tochio, N.]]
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[[Category: Ggc domain]]
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[[Category: Hydrolase]]

Revision as of 10:15, 25 December 2013

Template:STRUCTURE 2rtx

Contents

Solution structure of the GGQ domain of YaeJ protein from Escherichia coli

Template:ABSTRACT PUBMED 24322300

Function

[ARFB_ECOLI] Rescues stalled ribosomes. Can hydrolyze peptidyl-tRNA on ribosomes stalled by both non-stop mRNAs and mRNAs that contain rare codon clusters. May function as a complementary rescue system when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system or the alternative ribosome-rescue factor A.[1] [2]

About this Structure

2rtx is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • Kogure H, Handa Y, Nagata M, Kanai N, Guntert P, Kubota K, Nameki N. Identification of residues required for stalled-ribosome rescue in the codon-independent release factor YaeJ. Nucleic Acids Res. 2013 Dec 9. PMID:24322300 doi:http://dx.doi.org/10.1093/nar/gkt1280
  1. ↑ Chadani Y, Ono K, Kutsukake K, Abo T. Escherichia coli YaeJ protein mediates a novel ribosome-rescue pathway distinct from SsrA- and ArfA-mediated pathways. Mol Microbiol. 2011 May;80(3):772-85. doi: 10.1111/j.1365-2958.2011.07607.x. Epub, 2011 Mar 21. PMID:21418110 doi:http://dx.doi.org/10.1111/j.1365-2958.2011.07607.x
  2. ↑ Handa Y, Inaho N, Nameki N. YaeJ is a novel ribosome-associated protein in Escherichia coli that can hydrolyze peptidyl-tRNA on stalled ribosomes. Nucleic Acids Res. 2011 Mar;39(5):1739-48. doi: 10.1093/nar/gkq1097. Epub 2010, Nov 3. PMID:21051357 doi:http://dx.doi.org/10.1093/nar/gkq1097

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