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4mhg

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4mhg| PDB=4mhg | SCENE= }}
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===Crystal structure of ETV6 bound to a specific DNA sequence===
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{{ABSTRACT_PUBMED_24333486}}
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The entry 4mhg is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/ETV6_MOUSE ETV6_MOUSE]] Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'.
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Authors: Chan, A.C., De, S., Coyne III, H.J., Okon, M., Murphy, M.E., Graves, B.J., McIntosh, L.P.
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==About this Structure==
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[[4mhg]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHG OCA].
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Description: Crystal structure of ETV6 bound to a specific DNA sequence
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==Reference==
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<ref group="xtra">PMID:024333486</ref><references group="xtra"/><references/>
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[[Category: Chan, A C.]]
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[[Category: De, S.]]
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[[Category: Graves, B J.]]
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[[Category: III, H J.Coyne.]]
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[[Category: McIntosh, L P.]]
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[[Category: Murphy, M E.]]
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[[Category: Okon, M.]]
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[[Category: Ets domain]]
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[[Category: Transcription factor]]
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[[Category: Transcription-dna complex]]

Revision as of 10:04, 8 January 2014

Template:STRUCTURE 4mhg

Contents

Crystal structure of ETV6 bound to a specific DNA sequence

Template:ABSTRACT PUBMED 24333486

Function

[ETV6_MOUSE] Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'.

About this Structure

4mhg is a 3 chain structure. Full crystallographic information is available from OCA.

Reference

  • De S, Chan AC, Coyne HJ 3rd, Bhachech N, Hermsdorf U, Okon M, Murphy ME, Graves BJ, McIntosh LP. Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6. J Mol Biol. 2013 Dec 11. pii: S0022-2836(13)00747-X. doi:, 10.1016/j.jmb.2013.11.031. PMID:24333486 doi:http://dx.doi.org/10.1016/j.jmb.2013.11.031

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OCA

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