4mhg
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4mhg| PDB=4mhg | SCENE= }} | |
| + | ===Crystal structure of ETV6 bound to a specific DNA sequence=== | ||
| + | {{ABSTRACT_PUBMED_24333486}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/ETV6_MOUSE ETV6_MOUSE]] Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. | ||
| - | + | ==About this Structure== | |
| + | [[4mhg]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHG OCA]. | ||
| - | + | ==Reference== | |
| + | <ref group="xtra">PMID:024333486</ref><references group="xtra"/><references/> | ||
| + | [[Category: Chan, A C.]] | ||
| + | [[Category: De, S.]] | ||
| + | [[Category: Graves, B J.]] | ||
| + | [[Category: III, H J.Coyne.]] | ||
| + | [[Category: McIntosh, L P.]] | ||
| + | [[Category: Murphy, M E.]] | ||
| + | [[Category: Okon, M.]] | ||
| + | [[Category: Ets domain]] | ||
| + | [[Category: Transcription factor]] | ||
| + | [[Category: Transcription-dna complex]] | ||
Revision as of 10:04, 8 January 2014
Contents |
Crystal structure of ETV6 bound to a specific DNA sequence
Template:ABSTRACT PUBMED 24333486
Function
[ETV6_MOUSE] Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'.
About this Structure
4mhg is a 3 chain structure. Full crystallographic information is available from OCA.
Reference
- De S, Chan AC, Coyne HJ 3rd, Bhachech N, Hermsdorf U, Okon M, Murphy ME, Graves BJ, McIntosh LP. Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6. J Mol Biol. 2013 Dec 11. pii: S0022-2836(13)00747-X. doi:, 10.1016/j.jmb.2013.11.031. PMID:24333486 doi:http://dx.doi.org/10.1016/j.jmb.2013.11.031
