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4nc3
From Proteopedia
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| - | + | {{STRUCTURE_4nc3| PDB=4nc3 | SCENE= }} | |
| + | ===Crystal structure of the 5-HT2B receptor solved using serial femtosecond crystallography in lipidic cubic phase.=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/5HT2B_HUMAN 5HT2B_HUMAN]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior. | ||
| - | + | ==About this Structure== | |
| - | + | [[4nc3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NC3 OCA]. | |
| - | + | [[Category: Barty, A.]] | |
| + | [[Category: Basu, S.]] | ||
| + | [[Category: Beyerlein, K R.]] | ||
| + | [[Category: Boutet, S.]] | ||
| + | [[Category: Caffrey, M.]] | ||
| + | [[Category: Chapman, H N.]] | ||
| + | [[Category: Cherezov, V.]] | ||
| + | [[Category: Fromme, P.]] | ||
| + | [[Category: Fromme, R.]] | ||
| + | [[Category: GPCR, GPCR Network.]] | ||
| + | [[Category: Gati, C.]] | ||
| + | [[Category: Grotjohann, I.]] | ||
| + | [[Category: Han, G W.]] | ||
| + | [[Category: James, D.]] | ||
| + | [[Category: Katritch, V.]] | ||
| + | [[Category: Kirian, R A.]] | ||
| + | [[Category: Koglin, J E.]] | ||
| + | [[Category: Kupitz, C.]] | ||
| + | [[Category: Li, D.]] | ||
| + | [[Category: Liu, W.]] | ||
| + | [[Category: Messerschmidt, M.]] | ||
| + | [[Category: Nelson, G.]] | ||
| + | [[Category: Rendek, K N.]] | ||
| + | [[Category: Seibert, M M.]] | ||
| + | [[Category: Shah, S T.A.]] | ||
| + | [[Category: Spence, J C.H.]] | ||
| + | [[Category: Stevens, R C.]] | ||
| + | [[Category: Wacker, D.]] | ||
| + | [[Category: Wang, C.]] | ||
| + | [[Category: Wang, D.]] | ||
| + | [[Category: Weierstall, U.]] | ||
| + | [[Category: White, T A.]] | ||
| + | [[Category: Williams, G J.]] | ||
| + | [[Category: Zatsepin, N A.]] | ||
| + | [[Category: Electron transport]] | ||
| + | [[Category: Ergotamine]] | ||
| + | [[Category: Free electron laser]] | ||
| + | [[Category: Gpcr]] | ||
| + | [[Category: Gpcr network]] | ||
| + | [[Category: Human 5ht2b receptor]] | ||
| + | [[Category: Lipidic cubic phase]] | ||
| + | [[Category: Membrane]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Novel protein engineering]] | ||
| + | [[Category: Psi-biology]] | ||
| + | [[Category: Serial femtosecond crystallography]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Structural genomic]] | ||
Revision as of 10:42, 18 December 2013
Crystal structure of the 5-HT2B receptor solved using serial femtosecond crystallography in lipidic cubic phase.
Function
[5HT2B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
About this Structure
4nc3 is a 1 chain structure. Full crystallographic information is available from OCA.
Categories: Barty, A. | Basu, S. | Beyerlein, K R. | Boutet, S. | Caffrey, M. | Chapman, H N. | Cherezov, V. | Fromme, P. | Fromme, R. | GPCR, GPCR Network. | Gati, C. | Grotjohann, I. | Han, G W. | James, D. | Katritch, V. | Kirian, R A. | Koglin, J E. | Kupitz, C. | Li, D. | Liu, W. | Messerschmidt, M. | Nelson, G. | Rendek, K N. | Seibert, M M. | Shah, S T.A. | Spence, J C.H. | Stevens, R C. | Wacker, D. | Wang, C. | Wang, D. | Weierstall, U. | White, T A. | Williams, G J. | Zatsepin, N A. | Electron transport | Ergotamine | Free electron laser | Gpcr | Gpcr network | Human 5ht2b receptor | Lipidic cubic phase | Membrane | Membrane protein | Novel protein engineering | Psi-biology | Serial femtosecond crystallography | Signaling protein | Structural genomic
