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4nk0

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m (Protected "4nk0" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4nk0| PDB=4nk0 | SCENE= }}
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===Human histidine triad nucleotide-binding protein 2 (hHINT2) in P212121 space group at 2.02 A===
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The entry 4nk0 is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/HINT2_HUMAN HINT2_HUMAN]] Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity.<ref>PMID:16762638</ref> <ref>PMID:18653718</ref>
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Authors: Dolot, R.M., Wlodarczyk, A., Bujacz, G.D., Nawrot, B.
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==About this Structure==
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[[4nk0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NK0 OCA].
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Description: Human histidine triad nucleotide-binding protein 2 (hHINT2) in P212121 space group at 2.02 A
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Bujacz, G D.]]
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[[Category: Dolot, R M.]]
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[[Category: Nawrot, B.]]
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[[Category: Wlodarczyk, A.]]
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[[Category: Dna binding protein]]
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[[Category: Hint]]
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[[Category: Histidine triad]]
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[[Category: Hit]]
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[[Category: Hydrolase]]
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[[Category: Phosphoramidase]]

Revision as of 13:54, 11 December 2013

Template:STRUCTURE 4nk0

Contents

Human histidine triad nucleotide-binding protein 2 (hHINT2) in P212121 space group at 2.02 A

Function

[HINT2_HUMAN] Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity.[1] [2]

About this Structure

4nk0 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Martin J, Magnino F, Schmidt K, Piguet AC, Lee JS, Semela D, St-Pierre MV, Ziemiecki A, Cassio D, Brenner C, Thorgeirsson SS, Dufour JF. Hint2, a mitochondrial apoptotic sensitizer down-regulated in hepatocellular carcinoma. Gastroenterology. 2006 Jun;130(7):2179-88. PMID:16762638 doi:10.1053/j.gastro.2006.03.024
  2. ↑ Lenglet S, Antigny F, Vetterli L, Dufour JF, Rossier MF. Hint2 is expressed in the mitochondria of H295R cells and is involved in steroidogenesis. Endocrinology. 2008 Nov;149(11):5461-9. doi: 10.1210/en.2008-0400. Epub 2008 Jul , 24. PMID:18653718 doi:10.1210/en.2008-0400

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OCA

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