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4nk0
From Proteopedia
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| - | + | {{STRUCTURE_4nk0| PDB=4nk0 | SCENE= }} | |
| + | ===Human histidine triad nucleotide-binding protein 2 (hHINT2) in P212121 space group at 2.02 A=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/HINT2_HUMAN HINT2_HUMAN]] Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity.<ref>PMID:16762638</ref> <ref>PMID:18653718</ref> | ||
| - | + | ==About this Structure== | |
| + | [[4nk0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NK0 OCA]. | ||
| - | + | ==Reference== | |
| + | <references group="xtra"/><references/> | ||
| + | [[Category: Bujacz, G D.]] | ||
| + | [[Category: Dolot, R M.]] | ||
| + | [[Category: Nawrot, B.]] | ||
| + | [[Category: Wlodarczyk, A.]] | ||
| + | [[Category: Dna binding protein]] | ||
| + | [[Category: Hint]] | ||
| + | [[Category: Histidine triad]] | ||
| + | [[Category: Hit]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Phosphoramidase]] | ||
Revision as of 13:54, 11 December 2013
Contents |
Human histidine triad nucleotide-binding protein 2 (hHINT2) in P212121 space group at 2.02 A
Function
[HINT2_HUMAN] Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity.[1] [2]
About this Structure
4nk0 is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Martin J, Magnino F, Schmidt K, Piguet AC, Lee JS, Semela D, St-Pierre MV, Ziemiecki A, Cassio D, Brenner C, Thorgeirsson SS, Dufour JF. Hint2, a mitochondrial apoptotic sensitizer down-regulated in hepatocellular carcinoma. Gastroenterology. 2006 Jun;130(7):2179-88. PMID:16762638 doi:10.1053/j.gastro.2006.03.024
- ↑ Lenglet S, Antigny F, Vetterli L, Dufour JF, Rossier MF. Hint2 is expressed in the mitochondria of H295R cells and is involved in steroidogenesis. Endocrinology. 2008 Nov;149(11):5461-9. doi: 10.1210/en.2008-0400. Epub 2008 Jul , 24. PMID:18653718 doi:10.1210/en.2008-0400
