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4npy

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'''Unreleased structure'''
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{{STRUCTURE_4npy| PDB=4npy | SCENE= }}
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===Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody===
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{{ABSTRACT_PUBMED_24278016}}
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The entry 4npy is ON HOLD
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==About this Structure==
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[[4npy]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NPY OCA].
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Authors: Julien, J.-P., Diwanji, D.C., Wilson, I.A.
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==Reference==
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<ref group="xtra">PMID:024278016</ref><references group="xtra"/><references/>
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Description: Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody
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[[Category: Diwanji, D C.]]
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[[Category: Julien, J P.]]
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[[Category: Wilson, I A.]]
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[[Category: Anti-hiv antibody precursor]]
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[[Category: Hiv env gp120]]
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[[Category: Igg-fold]]
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[[Category: Immune system]]

Revision as of 13:37, 11 December 2013

Template:STRUCTURE 4npy

Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody

Template:ABSTRACT PUBMED 24278016

About this Structure

4npy is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, Simen BB, St John EP, Chan-Hui PY, Swiderek K, Kleinstein SH, Alter G, Seaman MS, Chakraborty AK, Koller D, Wilson IA, Church GM, Burton DR, Poignard P. The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies. PLoS Pathog. 2013 Nov;9(11):e1003754. doi: 10.1371/journal.ppat.1003754. Epub, 2013 Nov 21. PMID:24278016 doi:http://dx.doi.org/10.1371/journal.ppat.1003754

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OCA

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