4m17

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==About this Structure==
==About this Structure==
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[[4m17]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M17 OCA].
+
[[4m17]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M17 OCA].
==Reference==
==Reference==
<ref group="xtra">PMID:024224757</ref><references group="xtra"/><references/>
<ref group="xtra">PMID:024224757</ref><references group="xtra"/><references/>
 +
[[Category: Human]]
[[Category: Allen, K.]]
[[Category: Allen, K.]]
[[Category: Cafarella, T R.]]
[[Category: Cafarella, T R.]]

Revision as of 12:23, 11 December 2013

Template:STRUCTURE 4m17

Contents

Crystal Structure of Surfactant Protein-D D325A/R343V mutant

Template:ABSTRACT PUBMED 24224757

Function

[SFTPD_HUMAN] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

About this Structure

4m17 is a 12 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Goh BC, Rynkiewicz MJ, Cafarella TR, White MR, Hartshorn KL, Allen K, Crouch EC, Calin O, Seeberger PH, Schulten K, Seaton BA. Molecular mechanisms of inhibition of influenza by surfactant protein d revealed by large-scale molecular dynamics simulation. Biochemistry. 2013 Nov 26;52(47):8527-38. doi: 10.1021/bi4010683. Epub 2013 Nov, 13. PMID:24224757 doi:http://dx.doi.org/10.1021/bi4010683

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