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2r9s

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[[Image:2r9s.gif|left|200px]]<br /><applet load="2r9s" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2r9s.gif|left|200px]]
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caption="2r9s, resolution 2.400&Aring;" />
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'''c-Jun N-terminal Kinase 3 with 3,5-Disubstituted Quinoline inhibitor'''<br />
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{{Structure
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|PDB= 2r9s |SIZE=350|CAPTION= <scene name='initialview01'>2r9s</scene>, resolution 2.400&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=255:N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide'>255</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=TFA:TRIFLUOROACETYL+GROUP'>TFA</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24]
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|GENE= MAPK10, JNK3, JNK3A, PRKM10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''c-Jun N-terminal Kinase 3 with 3,5-Disubstituted Quinoline inhibitor'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2R9S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=255:'>255</scene>, <scene name='pdbligand=UNX:'>UNX</scene>, <scene name='pdbligand=TFA:'>TFA</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R9S OCA].
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2R9S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R9S OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]
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[[Category: transferase]]
[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:45:45 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:33:53 2008''

Revision as of 16:33, 20 March 2008

Image:2r9s.gif


PDB ID 2r9s

Drag the structure with the mouse to rotate
, resolution 2.400Å
Ligands: , , and
Gene: MAPK10, JNK3, JNK3A, PRKM10 (Homo sapiens)
Activity: Mitogen-activated protein kinase, with EC number 2.7.11.24
Coordinates: save as pdb, mmCIF, xml



c-Jun N-terminal Kinase 3 with 3,5-Disubstituted Quinoline inhibitor


Disease

Known diseases associated with this structure: Epileptic encephalopathy, Lennox-Gastaut type OMIM:[602897]

About this Structure

2R9S is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 18:33:53 2008

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