4c8d
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of JmjC domain of human histone 3 Lysine-specific demethylase 3B (KDM3B)== | |
| - | + | <StructureSection load='4c8d' size='340' side='right' caption='[[4c8d]], [[Resolution|resolution]] 2.18Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | ==Function== | + | <table><tr><td colspan='2'>[[4c8d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C8D FirstGlance]. <br> |
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c8d RCSB], [http://www.ebi.ac.uk/pdbsum/4c8d PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/KDM3B_HUMAN KDM3B_HUMAN]] Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.<ref>PMID:16603237</ref> | [[http://www.uniprot.org/uniprot/KDM3B_HUMAN KDM3B_HUMAN]] Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.<ref>PMID:16603237</ref> | ||
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | <references | + | |
[[Category: Human]] | [[Category: Human]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Crawley, L | + | [[Category: Crawley, L]] |
| - | [[Category: Delft, F von | + | [[Category: Delft, F von]] |
| - | [[Category: Edwards, A | + | [[Category: Edwards, A]] |
| - | [[Category: Gileadi, C | + | [[Category: Gileadi, C]] |
| - | [[Category: Goubin, S | + | [[Category: Goubin, S]] |
| - | [[Category: Johansson, C | + | [[Category: Johansson, C]] |
| - | [[Category: Krojer, T | + | [[Category: Krojer, T]] |
| - | [[Category: Oppermann, U | + | [[Category: Oppermann, U]] |
| - | [[Category: Szykowska, A | + | [[Category: Szykowska, A]] |
| - | [[Category: Vollmar, M | + | [[Category: Vollmar, M]] |
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 14:28, 25 December 2014
Crystal structure of JmjC domain of human histone 3 Lysine-specific demethylase 3B (KDM3B)
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Categories: Human | Arrowsmith, C H | Bountra, C | Crawley, L | Delft, F von | Edwards, A | Gileadi, C | Goubin, S | Johansson, C | Krojer, T | Oppermann, U | Szykowska, A | Vollmar, M | Oxidoreductase
