2reb

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[[Image:2reb.gif|left|200px]]<br /><applet load="2reb" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2reb.gif|left|200px]]
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caption="2reb, resolution 2.3&Aring;" />
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'''THE STRUCTURE OF THE E. COLI RECA PROTEIN MONOMER AND POLYMER'''<br />
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{{Structure
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|PDB= 2reb |SIZE=350|CAPTION= <scene name='initialview01'>2reb</scene>, resolution 2.3&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY= [http://en.wikipedia.org/wiki/Deleted_entry Deleted entry], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.99.37 3.4.99.37]
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|GENE=
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}}
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'''THE STRUCTURE OF THE E. COLI RECA PROTEIN MONOMER AND POLYMER'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2REB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Active as [http://en.wikipedia.org/wiki/Deleted_entry Deleted entry], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.99.37 3.4.99.37] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2REB OCA].
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2REB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2REB OCA].
==Reference==
==Reference==
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The structure of the E. coli recA protein monomer and polymer., Story RM, Weber IT, Steitz TA, Nature. 1992 Jan 23;355(6358):318-25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1731246 1731246]
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The structure of the E. coli recA protein monomer and polymer., Story RM, Weber IT, Steitz TA, Nature. 1992 Jan 23;355(6358):318-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1731246 1731246]
[[Category: Deleted entry]]
[[Category: Deleted entry]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: self-cleavage stimulation]]
[[Category: self-cleavage stimulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:46:45 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:35:19 2008''

Revision as of 16:35, 20 March 2008

Image:2reb.gif


PDB ID 2reb

Drag the structure with the mouse to rotate
, resolution 2.3Å
Activity: Deleted entry, with EC number 3.4.99.37
Coordinates: save as pdb, mmCIF, xml



THE STRUCTURE OF THE E. COLI RECA PROTEIN MONOMER AND POLYMER


Overview

The crystal structure of the recA protein from Escherichia coli at 2.3-A resolution reveals a major domain that binds ADP and probably single- and double-stranded DNA. Two smaller subdomains at the N and C termini protrude from the protein and respectively stabilize a 6(1) helical polymer of protein subunits and interpolymer bundles. This polymer structure closely resembles that of recA/DNA filaments determined by electron microscopy. Mutations in recA protein that enhance coprotease, DNA-binding and/or strand-exchange activity can be explained if the interpolymer interactions in the crystal reflect a regulatory mechanism in vivo.

About this Structure

2REB is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

The structure of the E. coli recA protein monomer and polymer., Story RM, Weber IT, Steitz TA, Nature. 1992 Jan 23;355(6358):318-25. PMID:1731246

Page seeded by OCA on Thu Mar 20 18:35:19 2008

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