2rf0

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[[Image:2rf0.jpg|left|200px]]<br /><applet load="2rf0" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2rf0.jpg|left|200px]]
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caption="2rf0, resolution 2.00&Aring;" />
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'''Crystal structure of human mixed lineage kinase MAP3K10 SH3 domain'''<br />
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{{Structure
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|PDB= 2rf0 |SIZE=350|CAPTION= <scene name='initialview01'>2rf0</scene>, resolution 2.00&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase_kinase_kinase Mitogen-activated protein kinase kinase kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.25 2.7.11.25]
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|GENE= MAP3K10, MLK2, MST ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal structure of human mixed lineage kinase MAP3K10 SH3 domain'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2RF0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase_kinase_kinase Mitogen-activated protein kinase kinase kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.25 2.7.11.25] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RF0 OCA].
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2RF0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RF0 OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase kinase kinase]]
[[Category: Mitogen-activated protein kinase kinase kinase]]
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[[Category: sgc]]
[[Category: sgc]]
[[Category: sh3 domain]]
[[Category: sh3 domain]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
[[Category: tkl kinase]]
[[Category: tkl kinase]]
[[Category: transferase]]
[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:46:48 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:35:28 2008''

Revision as of 16:35, 20 March 2008

Image:2rf0.jpg


PDB ID 2rf0

Drag the structure with the mouse to rotate
, resolution 2.00Å
Ligands:
Gene: MAP3K10, MLK2, MST (Homo sapiens)
Activity: Mitogen-activated protein kinase kinase kinase, with EC number 2.7.11.25
Coordinates: save as pdb, mmCIF, xml



Crystal structure of human mixed lineage kinase MAP3K10 SH3 domain


Disease

Known disease associated with this structure: Leukemia, transient, of Down syndrome OMIM:[159595]

About this Structure

2RF0 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 18:35:28 2008

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OCA

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