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| - | == | + | == Trypanothione Synthetase == |
| - | + | <scene name='44/449739/Trypanothione_synthetase/1'>Trypnaothione Synthetase</scene> is an enzyme involved in the synthesis of a unique thiol trypanothione. Trypanothione synthetase is absent in human thus making it a potential drug target for anti-trypanosomatids drugs. The protein is comprised of <scene name='44/449739/Trypanothione_synthetase/2'>two distinct domains</scene> having independent functions. The N-terminal domain also known as a cysteine, histidine-dependent amidohydrolase/peptidase amidase (CHAP) or the amindase domain is a cysteine protease while the C-terminal domain or the synthase domain carry out ATP dependent synthesis of trypanothione from glutathione and glutathionyl spermidine. | |
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| - | + | <Structure load='2vps' size='500' frame='true' align='right' caption='tst of loading a molecule' scene='Insert optional scene name here' /> | |
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Current revision
Trypanothione Synthetase
is an enzyme involved in the synthesis of a unique thiol trypanothione. Trypanothione synthetase is absent in human thus making it a potential drug target for anti-trypanosomatids drugs. The protein is comprised of having independent functions. The N-terminal domain also known as a cysteine, histidine-dependent amidohydrolase/peptidase amidase (CHAP) or the amindase domain is a cysteine protease while the C-terminal domain or the synthase domain carry out ATP dependent synthesis of trypanothione from glutathione and glutathionyl spermidine.
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