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4ci8

From Proteopedia

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m (Protected "4ci8" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4ci8| PDB=4ci8 | SCENE= }}
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===Crystal structure of the tandem atypical beta-propeller domain of EML1===
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{{ABSTRACT_PUBMED_24706829}}
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The entry 4ci8 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/EMAL1_HUMAN EMAL1_HUMAN]] May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity).
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Authors: Richards, M.W., Bayliss, R.
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==About this Structure==
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[[4ci8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CI8 OCA].
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Description: Crystal structure of the tandem atypical beta-propeller domain of EML1
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==Reference==
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<ref group="xtra">PMID:024706829</ref><references group="xtra"/><references/>
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[[Category: Bayliss, R.]]
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[[Category: Richards, M W.]]
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[[Category: Beta propeller]]
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[[Category: Eml1]]
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[[Category: Eml4-alk]]
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[[Category: Hsp90 inhibitor]]
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[[Category: Structural protein]]
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[[Category: Tubulin-binding]]

Revision as of 09:50, 16 April 2014

Template:STRUCTURE 4ci8

Contents

Crystal structure of the tandem atypical beta-propeller domain of EML1

Template:ABSTRACT PUBMED 24706829

Function

[EMAL1_HUMAN] May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity).

About this Structure

4ci8 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Richards MW, Law EW, Rennalls LP, Busacca S, O'Regan L, Fry AM, Fennell DA, Bayliss R. Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical beta-propeller domain. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5195-200. doi:, 10.1073/pnas.1322892111. Epub 2014 Mar 24. PMID:24706829 doi:http://dx.doi.org/10.1073/pnas.1322892111

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OCA

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