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2uue

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[[Image:2uue.gif|left|200px]]<br /><applet load="2uue" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2uue.gif|left|200px]]
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caption="2uue, resolution 2.06&Aring;" />
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'''REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS'''<br />
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{{Structure
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|PDB= 2uue |SIZE=350|CAPTION= <scene name='initialview01'>2uue</scene>, resolution 2.06&Aring;
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|SITE= <scene name='pdbsite=AC1:Nh2+Binding+Site+For+Chain+F'>AC1</scene>
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|LIGAND= <scene name='pdbligand=MTZ:4-METHYL-5-{(2E)-2-[(4-MORPHOLIN-4-YLPHENYL)IMINO]-2,5-DIHYDROPYRIMIDIN-4-YL}-1,3-THIAZOL-2-AMINE'>MTZ</scene> and <scene name='pdbligand=GVC:1-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID'>GVC</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
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|GENE=
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}}
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'''REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS'''
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==About this Structure==
==About this Structure==
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2UUE is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MTZ:'>MTZ</scene> and <scene name='pdbligand=GVC:'>GVC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 2C5T. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Known structural/functional Site: <scene name='pdbsite=AC1:Nh2+Binding+Site+For+Chain+F'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UUE OCA].
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2UUE is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 2C5T. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UUE OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: transferase]]
[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:50:20 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:39:48 2008''

Revision as of 16:39, 20 March 2008

Image:2uue.gif


PDB ID 2uue

Drag the structure with the mouse to rotate
, resolution 2.06Å
Sites:
Ligands: and
Activity: Non-specific serine/threonine protein kinase, with EC number 2.7.11.1
Coordinates: save as pdb, mmCIF, xml



REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS


About this Structure

2UUE is a Protein complex structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entry 2C5T. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 18:39:48 2008

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