4njp
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4njp| PDB=4njp | SCENE= }} | {{STRUCTURE_4njp| PDB=4njp | SCENE= }} | ||
===Proteolysis inside the membrane is a rate-governed reaction not Driven by substrate affinity=== | ===Proteolysis inside the membrane is a rate-governed reaction not Driven by substrate affinity=== | ||
| + | {{ABSTRACT_PUBMED_24315097}} | ||
==Function== | ==Function== | ||
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==Reference== | ==Reference== | ||
| - | <references group="xtra"/><references/> | + | <ref group="xtra">PMID:024315097</ref><references group="xtra"/><references/> |
[[Category: Rhomboid protease]] | [[Category: Rhomboid protease]] | ||
[[Category: Baker, R P.]] | [[Category: Baker, R P.]] | ||
Revision as of 10:47, 1 January 2014
Contents |
Proteolysis inside the membrane is a rate-governed reaction not Driven by substrate affinity
Template:ABSTRACT PUBMED 24315097
Function
[GLPG_ECOLI] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.[1] [2]
About this Structure
4njp is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Dickey SW, Baker RP, Cho S, Urban S. Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity. Cell. 2013 Dec 5;155(6):1270-81. doi: 10.1016/j.cell.2013.10.053. PMID:24315097 doi:http://dx.doi.org/10.1016/j.cell.2013.10.053
- ↑ Wu Z, Yan N, Feng L, Oberstein A, Yan H, Baker RP, Gu L, Jeffrey PD, Urban S, Shi Y. Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry. Nat Struct Mol Biol. 2006 Dec;13(12):1084-91. Epub 2006 Nov 10. PMID:17099694 doi:10.1038/nsmb1179
- ↑ Maegawa S, Ito K, Akiyama Y. Proteolytic action of GlpG, a rhomboid protease in the Escherichia coli cytoplasmic membrane. Biochemistry. 2005 Oct 18;44(41):13543-52. PMID:16216077 doi:10.1021/bi051363k
