P73
From Proteopedia
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{{STRUCTURE_2xwc| PDB=2xwc | SIZE=400| SCENE= |right|CAPTION=Monomer of the dimeric human p73 DNA-binding domain complex with Tris, glycerol and Zn+2 ion (grey), [[2xwc]] }} | {{STRUCTURE_2xwc| PDB=2xwc | SIZE=400| SCENE= |right|CAPTION=Monomer of the dimeric human p73 DNA-binding domain complex with Tris, glycerol and Zn+2 ion (grey), [[2xwc]] }} | ||
| - | '''p73''' is a protein related to p53 tumor | + | '''p73''' is a protein related to p53 tumor suppressor. It is involved in cell cycle regulation and induction of apoptosis. P73 has several variants differing in their C- or N-terminal. P73 contains DNA-binding domain (DBD residues 112-312); tetramerization domain (TD residues 351-398). |
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{{TOC limit|limit=2}} | {{TOC limit|limit=2}} | ||
== 3D Structures of p73 == | == 3D Structures of p73 == | ||
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| + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
[[1cok]] – hp73 C terminal – human – NMR | [[1cok]] – hp73 C terminal – human – NMR | ||
| - | [[2kby]] – hp73 | + | [[2kby]] – hp73 TD – NMR |
| - | [[2wqi]], [[2wqj]], [[2wtt]] - hp73 | + | [[2wqi]], [[2wqj]], [[2wtt]] - hp73 TD |
| - | [[2xwc]] – hp73 | + | [[2xwc]] – hp73 DBD (mutant)<br /> |
| + | [[3vd0]], [[3dv1]], [[3dv2]], [[4g82]], [[4g83]], [[4guo]], [[4guq]] – hp73 DBD + DNA<br /> | ||
| + | [[4a63]] – hp73 DBD + apoptosis stimulating of p53 protein<br /> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:31, 1 April 2014
p73 is a protein related to p53 tumor suppressor. It is involved in cell cycle regulation and induction of apoptosis. P73 has several variants differing in their C- or N-terminal. P73 contains DNA-binding domain (DBD residues 112-312); tetramerization domain (TD residues 351-398).
Contents |
3D Structures of p73
Updated on 01-April-2014
1cok – hp73 C terminal – human – NMR
2kby – hp73 TD – NMR
2xwc – hp73 DBD (mutant)
3vd0, 3dv1, 3dv2, 4g82, 4g83, 4guo, 4guq – hp73 DBD + DNA
4a63 – hp73 DBD + apoptosis stimulating of p53 protein
