Sandbox Reserved 825
From Proteopedia
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=='''FRB Domain'''== | =='''FRB Domain'''== | ||
| - | The mammalian target of rapamycin (mTOR) is a protein that is intricately involved in signaling pathways controlling cell growth. Rapamycin is a natural product that binds and inhibits mTOR function by interacting with its FKBP-rapamycin-binding (FRB) domain | + | The mammalian target of rapamycin ('''mTOR''') is a protein that is intricately involved in signaling pathways controlling cell growth. '''Rapamycin''' is a natural product that binds and inhibits mTOR function by interacting with its '''FKBP-rapamycin-binding (FRB) domain''' |
mTOR is highly conserved across all eukaryotes, with 40–60% amino-acid sequence identity. | mTOR is highly conserved across all eukaryotes, with 40–60% amino-acid sequence identity. | ||
Revision as of 13:25, 30 December 2013
| This Sandbox is Reserved from 06/12/2018, through 30/06/2019 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1480 through Sandbox Reserved 1543. |
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FRB Domain
The mammalian target of rapamycin (mTOR) is a protein that is intricately involved in signaling pathways controlling cell growth. Rapamycin is a natural product that binds and inhibits mTOR function by interacting with its FKBP-rapamycin-binding (FRB) domain
mTOR is highly conserved across all eukaryotes, with 40–60% amino-acid sequence identity.
