4cas

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{{STRUCTURE_4cas| PDB=4cas | SCENE= }}
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==Serial femtosecond crystallography structure of a photosynthetic reaction center==
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===Serial femtosecond crystallography structure of a photosynthetic reaction center===
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<StructureSection load='4cas' size='340' side='right' caption='[[4cas]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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{{ABSTRACT_PUBMED_24352554}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4cas]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Blastochloris_viridis Blastochloris viridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CAS FirstGlance]. <br>
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==Function==
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCL:BACTERIOCHLOROPHYLL+A'>BCL</scene>, <scene name='pdbligand=BPB:BACTERIOPHEOPHYTIN+B'>BPB</scene>, <scene name='pdbligand=DGA:DIACYL+GLYCEROL'>DGA</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MPG:1-MONOOLEOYL-RAC-GLYCEROL'>MPG</scene>, <scene name='pdbligand=MQ7:MENAQUINONE-7'>MQ7</scene>, <scene name='pdbligand=NS5:15-CIS-1,2-DIHYDRONEUROSPORENE'>NS5</scene>, <scene name='pdbligand=OTP:(2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-OCTAENYL+TRIHYDROGEN+DIPHOSPHATE'>OTP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cas OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cas RCSB], [http://www.ebi.ac.uk/pdbsum/4cas PDBsum]</span></td></tr>
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</table>
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== Function ==
[[http://www.uniprot.org/uniprot/RCEH_RHOVI RCEH_RHOVI]] The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. [[http://www.uniprot.org/uniprot/CYCR_RHOVI CYCR_RHOVI]] The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor. [[http://www.uniprot.org/uniprot/RCEM_RHOVI RCEM_RHOVI]] The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. [[http://www.uniprot.org/uniprot/RCEL_RHOVI RCEL_RHOVI]] The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
[[http://www.uniprot.org/uniprot/RCEH_RHOVI RCEH_RHOVI]] The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. [[http://www.uniprot.org/uniprot/CYCR_RHOVI CYCR_RHOVI]] The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor. [[http://www.uniprot.org/uniprot/RCEM_RHOVI RCEM_RHOVI]] The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. [[http://www.uniprot.org/uniprot/RCEL_RHOVI RCEL_RHOVI]] The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Serial femtosecond crystallography is an X-ray free-electron-laser-based method with considerable potential to have an impact on challenging problems in structural biology. Here we present X-ray diffraction data recorded from microcrystals of the Blastochloris viridis photosynthetic reaction centre to 2.8 A resolution and determine its serial femtosecond crystallography structure to 3.5 A resolution. Although every microcrystal is exposed to a dose of 33 MGy, no signs of X-ray-induced radiation damage are visible in this integral membrane protein structure.
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==About this Structure==
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Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography.,Johansson LC, Arnlund D, Katona G, White TA, Barty A, Deponte DP, Shoeman RL, Wickstrand C, Sharma A, Williams GJ, Aquila A, Bogan MJ, Caleman C, Davidsson J, Doak RB, Frank M, Fromme R, Galli L, Grotjohann I, Hunter MS, Kassemeyer S, Kirian RA, Kupitz C, Liang M, Lomb L, Malmerberg E, Martin AV, Messerschmidt M, Nass K, Redecke L, Seibert MM, Sjohamn J, Steinbrener J, Stellato F, Wang D, Wahlgren WY, Weierstall U, Westenhoff S, Zatsepin NA, Boutet S, Spence JC, Schlichting I, Chapman HN, Fromme P, Neutze R Nat Commun. 2013 Dec 19;4:2911. doi: 10.1038/ncomms3911. PMID:24352554<ref>PMID:24352554</ref>
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[[4cas]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Blastochloris_viridis Blastochloris viridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CAS OCA].
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==Reference==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<ref group="xtra">PMID:024352554</ref><references group="xtra"/><references/>
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</div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Blastochloris viridis]]
[[Category: Blastochloris viridis]]
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[[Category: Aquila, A.]]
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[[Category: Aquila, A]]
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[[Category: Arnlund, D.]]
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[[Category: Arnlund, D]]
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[[Category: Barty, A.]]
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[[Category: Barty, A]]
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[[Category: Bogan, M J.]]
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[[Category: Bogan, M J]]
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[[Category: Boutet, S.]]
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[[Category: Boutet, S]]
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[[Category: Caleman, C.]]
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[[Category: Caleman, C]]
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[[Category: Chapman, H N.]]
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[[Category: Chapman, H N]]
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[[Category: Davidsson, J.]]
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[[Category: Davidsson, J]]
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[[Category: DePonte, D P.]]
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[[Category: DePonte, D P]]
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[[Category: Doak, R B.]]
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[[Category: Doak, R B]]
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[[Category: Frank, M.]]
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[[Category: Frank, M]]
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[[Category: Fromme, P.]]
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[[Category: Fromme, P]]
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[[Category: Fromme, R.]]
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[[Category: Fromme, R]]
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[[Category: Galli, L.]]
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[[Category: Galli, L]]
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[[Category: Grotjohann, I.]]
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[[Category: Grotjohann, I]]
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[[Category: Hunter, M S.]]
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[[Category: Hunter, M S]]
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[[Category: Johansson, L C.]]
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[[Category: Johansson, L C]]
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[[Category: Kassemeyer, S.]]
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[[Category: Kassemeyer, S]]
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[[Category: Katona, G.]]
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[[Category: Katona, G]]
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[[Category: Kirian, R A.]]
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[[Category: Kirian, R A]]
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[[Category: Kupitz, C.]]
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[[Category: Kupitz, C]]
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[[Category: Liang, M.]]
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[[Category: Liang, M]]
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[[Category: Lomb, L.]]
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[[Category: Lomb, L]]
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[[Category: Malmerberg, E.]]
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[[Category: Malmerberg, E]]
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[[Category: Martin, A V.]]
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[[Category: Martin, A V]]
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[[Category: Messerschmidt, M.]]
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[[Category: Messerschmidt, M]]
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[[Category: Nass, K.]]
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[[Category: Nass, K]]
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[[Category: Neutze, R.]]
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[[Category: Neutze, R]]
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[[Category: Redecke, L.]]
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[[Category: Redecke, L]]
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[[Category: Schlichting, I.]]
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[[Category: Schlichting, I]]
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[[Category: Seibert, M M.]]
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[[Category: Seibert, M M]]
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[[Category: Sharma, A.]]
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[[Category: Sharma, A]]
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[[Category: Shoeman, R L.]]
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[[Category: Shoeman, R L]]
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[[Category: Sjohamn, J.]]
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[[Category: Sjohamn, J]]
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[[Category: Spence, J C.H.]]
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[[Category: Spence, J C.H]]
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[[Category: Steinbrener, J.]]
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[[Category: Steinbrener, J]]
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[[Category: Stellato, F.]]
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[[Category: Stellato, F]]
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[[Category: Wahlgren, W Y.]]
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[[Category: Wahlgren, W Y]]
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[[Category: Wang, D.]]
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[[Category: Wang, D]]
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[[Category: Weierstall, U.]]
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[[Category: Weierstall, U]]
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[[Category: Westenhoff, S.]]
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[[Category: Westenhoff, S]]
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[[Category: White, T A.]]
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[[Category: White, T A]]
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[[Category: Wickstrand, C.]]
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[[Category: Wickstrand, C]]
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[[Category: Williams, G J.]]
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[[Category: Williams, G J]]
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[[Category: Zatsepin, N A.]]
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[[Category: Zatsepin, N A]]
[[Category: Cell membrane]]
[[Category: Cell membrane]]
[[Category: Chromophore]]
[[Category: Chromophore]]

Revision as of 16:58, 25 December 2014

Serial femtosecond crystallography structure of a photosynthetic reaction center

4cas, resolution 3.50Å

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