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4ipp
From Proteopedia
(Difference between revisions)
Revision as of 08:22, 15 January 2014
tRNA-guanine-transglycosylase (TGT) mutant V262D APO-Structure
Function
[TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
About this Structure
4ipp is a 1 chain structure. Full crystallographic information is available from OCA.
Categories: Heine, A. | Klebe, G. | Neeb, M. | Guanine exchange enzyme | Preq1 | Transferase | Trna
