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4ipp

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4ipp| PDB=4ipp | SCENE= }}
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===tRNA-guanine-transglycosylase (TGT) mutant V262D APO-Structure===
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The entry 4ipp is ON HOLD until Jan 14 2015
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==Function==
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[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
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Authors: Neeb, M., Heine, A., Klebe, G.
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==About this Structure==
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[[4ipp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IPP OCA].
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Description: tRNA-guanine-transglycosylase (TGT) mutant V262D APO-Structure
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[[Category: Heine, A.]]
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[[Category: Klebe, G.]]
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[[Category: Neeb, M.]]
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[[Category: Guanine exchange enzyme]]
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[[Category: Preq1]]
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[[Category: Transferase]]
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[[Category: Trna]]

Revision as of 08:22, 15 January 2014

Template:STRUCTURE 4ipp

tRNA-guanine-transglycosylase (TGT) mutant V262D APO-Structure

Function

[TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]

About this Structure

4ipp is a 1 chain structure. Full crystallographic information is available from OCA.

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OCA

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