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4c8g
From Proteopedia
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{{STRUCTURE_4c8g| PDB=4c8g | SCENE= }} | {{STRUCTURE_4c8g| PDB=4c8g | SCENE= }} | ||
===IspF (Burkholderia cenocepacia) CMP complex=== | ===IspF (Burkholderia cenocepacia) CMP complex=== | ||
| + | {{ABSTRACT_PUBMED_24410837}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4c8g]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8G OCA]. | [[4c8g]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8G OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:024410837</ref><references group="xtra"/><references/> | ||
[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]] | [[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]] | ||
[[Category: Dawson, A.]] | [[Category: Dawson, A.]] | ||
Revision as of 06:23, 29 January 2014
Contents |
IspF (Burkholderia cenocepacia) CMP complex
Template:ABSTRACT PUBMED 24410837
Function
[ISPF_BURCJ] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).
About this Structure
4c8g is a 3 chain structure. Full crystallographic information is available from OCA.
Reference
- O Rourke PE, Kalinowska-T U Cik J, Fyfe PK, Dawson A, Hunter WN. Crystal structures of IspF from Plasmodium falciparum and Burkholderia cenocepacia: comparisons inform antimicrobial drug target assessment. BMC Struct Biol. 2014 Jan 10;14(1):1. PMID:24410837 doi:http://dx.doi.org/10.1186/1472-6807-14-1
