DNA ligase

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Line 56: Line 56:
[[3jsl]], [[3jsn]] - LigD adenylation domain – ''Staphylococcus aureus''<br />
[[3jsl]], [[3jsn]] - LigD adenylation domain – ''Staphylococcus aureus''<br />
-
[[3ba8]], [[3ba9]], [[3baa]], [[3bab]], [[3bac]], [[4eeq]], [[4efb]], [[4efe]] - EfLigD adenylation domain + NMN + inhibitor – ''Enterococcus faecalis''<br />
+
[[3ba8]], [[3ba9]], [[3baa]], [[3bab]], [[3bac]], [[4eeq]], [[4efb]], [[4efe]], [[4lh6]], [[4lh7]] - EfLigD adenylation domain + NMN + inhibitor – ''Enterococcus faecalis''<br />
[[1ta8]], [[1tae]] - EfLigD adenylation domain<br />
[[1ta8]], [[1tae]] - EfLigD adenylation domain<br />
[[1zau]] - MtLigD adenylation domain – ''Mycobacterium tuberculosis''<br />
[[1zau]] - MtLigD adenylation domain – ''Mycobacterium tuberculosis''<br />
Line 62: Line 62:
[[1v9p]], [[1dgs]] – LigD – ''Thermos filiformis''<br />
[[1v9p]], [[1dgs]] – LigD – ''Thermos filiformis''<br />
[[1b04]] – LigD adenylation domain (mutant) – ''Geobacillus stearothermophilus''<br />
[[1b04]] – LigD adenylation domain (mutant) – ''Geobacillus stearothermophilus''<br />
-
[[4glw]] – LigD A + NMN + inhibitor – ''Streptococcus pneumoniae''
+
[[4glw]] – LigD A + NMN + inhibitor – ''Streptococcus pneumoniae''<br />
 +
[[4glx]] – LigD + DNA + inhibitor - ''Escherichia coli''<br />
===LigD===
===LigD===

Revision as of 11:18, 26 February 2014

ATP-dependent DNA ligase complexed with ATP 2hix

Drag the structure with the mouse to rotate

REFERENCES

Elevated expression of DNA ligase I in human cancers., Sun DY, Urrabaz R, Nguyen M, Marty J, Stringer S, Cruz E, Medina-Gundrum L, Weitman S., Clinical Cancer Research. 2001; 7(12):4143-4148.
Replication failure, genome instability, and increased cancer susceptibility in mice with a point mutation in the DNA ligase I gene., Harrison C, Ketchen AM, Redhead NJ, O'Sullivan MJ, Melton DW., Cancer Research. 2002; 62(14):4065-4074.

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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