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2yxj
From Proteopedia
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| - | [[Image:2yxj.gif|left|200px]] | + | [[Image:2yxj.gif|left|200px]] |
| - | + | ||
| - | '''Crystal structure of Bcl-xL in complex with ABT-737''' | + | {{Structure |
| + | |PDB= 2yxj |SIZE=350|CAPTION= <scene name='initialview01'>2yxj</scene>, resolution 2.20Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=N3C:4-{4-[(4'-CHLOROBIPHENYL-2-YL)METHYL]PIPERAZIN-1-YL}-N-{[4-({(1R)-3-(DIMETHYLAMINO)-1-[(PHENYLTHIO)METHYL]PROPYL}AMINO)-3-NITROPHENYL]SULFONYL}BENZAMIDE'>N3C</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= Bcl-xL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | }} | ||
| + | |||
| + | '''Crystal structure of Bcl-xL in complex with ABT-737''' | ||
| + | |||
==About this Structure== | ==About this Structure== | ||
| - | 2YXJ is a [ | + | 2YXJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXJ OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: cancer therapeutic]] | [[Category: cancer therapeutic]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:50:08 2008'' |
Revision as of 16:50, 20 March 2008
| |||||||
| , resolution 2.20Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , and | ||||||
| Gene: | Bcl-xL (Homo sapiens) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of Bcl-xL in complex with ABT-737
About this Structure
2YXJ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:50:08 2008
Categories: Homo sapiens | Single protein | Colman, P M. | Czabotar, P E. | Deshayes, K. | Fairlie, W D. | Lee, E F. | Smith, B J. | Zobel, K. | CL | GOL | N3C | Apoptosis | Cancer therapeutic
