This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4k4o

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_4k4o| PDB=4k4o | SCENE= }}
+
==The DNA Gyrase B ATP binding domain of Enterococcus faecalis in complex with a small molecule inhibitor==
-
===The DNA Gyrase B ATP binding domain of Enterococcus faecalis in complex with a small molecule inhibitor===
+
<StructureSection load='4k4o' size='340' side='right' caption='[[4k4o]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4k4o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Entfa Entfa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K4O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K4O FirstGlance]. <br>
 +
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOO:6-FLUORO-4-[(3AR,6AR)-HEXAHYDROPYRROLO[3,4-B]PYRROL-5(1H)-YL]-N-METHYL-2-[(2-METHYLPYRIMIDIN-5-YL)OXY]-9H-PYRIMIDO[4,5-B]INDOL-8-AMINE'>DOO</scene>, <scene name='pdbligand=TBU:TERTIARY-BUTYL+ALCOHOL'>TBU</scene></td></tr>
 +
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EF_0005, gyrB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=226185 ENTFA])</td></tr>
 +
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k4o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k4o RCSB], [http://www.ebi.ac.uk/pdbsum/4k4o PDBsum]</span></td></tr>
 +
</table>
-
==Function==
+
==See Also==
-
[[http://www.uniprot.org/uniprot/Q839Z1_ENTFA Q839Z1_ENTFA]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity).[HAMAP-Rule:MF_01898]
+
*[[Gyrase|Gyrase]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
[[4k4o]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K4O OCA].
+
[[Category: Entfa]]
-
[[Category: Akers-Rodriguez, S.]]
+
[[Category: Akers-Rodriguez, S]]
-
[[Category: Bensen, D C.]]
+
[[Category: Bensen, D C]]
-
[[Category: Lam, T.]]
+
[[Category: Lam, T]]
-
[[Category: Tari, L W.]]
+
[[Category: Tari, L W]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Atp-binding domain]]
[[Category: Atp-binding domain]]

Revision as of 18:36, 21 December 2014

The DNA Gyrase B ATP binding domain of Enterococcus faecalis in complex with a small molecule inhibitor

4k4o, resolution 1.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools