354d

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[[Image:354d.jpg|left|200px]]<br /><applet load="354d" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:354d.jpg|left|200px]]
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caption="354d, resolution 1.500&Aring;" />
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'''STRUCTURE OF LOOP E FROM E. COLI 5S RRNA'''<br />
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{{Structure
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|PDB= 354d |SIZE=350|CAPTION= <scene name='initialview01'>354d</scene>, resolution 1.500&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=S:SULFUR ATOM'>S</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''STRUCTURE OF LOOP E FROM E. COLI 5S RRNA'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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354D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=S:'>S</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=354D OCA].
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354D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=354D OCA].
==Reference==
==Reference==
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Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain., Correll CC, Freeborn B, Moore PB, Steitz TA, Cell. 1997 Nov 28;91(5):705-12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9393863 9393863]
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Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain., Correll CC, Freeborn B, Moore PB, Steitz TA, Cell. 1997 Nov 28;91(5):705-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9393863 9393863]
[[Category: ]]
[[Category: ]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: u-rna]]
[[Category: u-rna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:02:16 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:54:52 2008''

Revision as of 16:54, 20 March 2008

Image:354d.jpg


PDB ID 354d

Drag the structure with the mouse to rotate
, resolution 1.500Å
Ligands: and
Coordinates: save as pdb, mmCIF, xml



STRUCTURE OF LOOP E FROM E. COLI 5S RRNA


Overview

Two new RNA structures portray how non-Watson-Crick base pairs and metal ions can produce a unique RNA shape suitable for recognition by proteins. The crystal structures of a 62 nt domain of E. coli 5S ribosomal RNA and a duplex dodecamer encompassing an internal loop E have been determined at 3.0 and 1.5 A, respectively. This loop E region is distorted by three "cross-strand purine stacks" and three novel, water-mediated noncanonical base pairs and stabilized by a four metal ion zipper. These features give its minor groove a unique hydrogen-bonding surface and make the adjacent major groove wide enough to permit recognition by the ribosomal protein L25, which is expected to bind to this surface.

About this Structure

354D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain., Correll CC, Freeborn B, Moore PB, Steitz TA, Cell. 1997 Nov 28;91(5):705-12. PMID:9393863 [[Category: ]]

Page seeded by OCA on Thu Mar 20 18:54:52 2008

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