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3b2u
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="3b2u" size="350" color="white" frame="true" align="right" spinBox="true" caption="3b2u, resolution 2.580Å" /> '''Crystal structure o...) |
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| - | [[Image:3b2u.jpg|left|200px]] | + | [[Image:3b2u.jpg|left|200px]] |
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| - | '''Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8''' | + | {{Structure |
| + | |PDB= 3b2u |SIZE=350|CAPTION= <scene name='initialview01'>3b2u</scene>, resolution 2.580Å | ||
| + | |SITE= <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+A+3281'>AC1</scene>, <scene name='pdbsite=AC2:Nag+Binding+Site+For+Residue+A+3282'>AC2</scene>, <scene name='pdbsite=AC3:Bma+Binding+Site+For+Residue+A+3283'>AC3</scene>, <scene name='pdbsite=AC4:Man+Binding+Site+For+Residue+A+3284'>AC4</scene>, <scene name='pdbsite=AC5:Nag+Binding+Site+For+Residue+A+4201'>AC5</scene>, <scene name='pdbsite=AC6:Nag+Binding+Site+For+Residue+B+3281'>AC6</scene>, <scene name='pdbsite=AC7:Nag+Binding+Site+For+Residue+B+3282'>AC7</scene>, <scene name='pdbsite=AC8:Bma+Binding+Site+For+Residue+B+3283'>AC8</scene>, <scene name='pdbsite=AC9:Nag+Binding+Site+For+Residue+B+3371'>AC9</scene>, <scene name='pdbsite=BC1:Nag+Binding+Site+For+Residue+B+4201'>BC1</scene>, <scene name='pdbsite=BC2:Nag+Binding+Site+For+Residue+E+3281'>BC2</scene>, <scene name='pdbsite=BC3:Nag+Binding+Site+For+Residue+E+3282'>BC3</scene>, <scene name='pdbsite=BC4:Bma+Binding+Site+For+Residue+E+3283'>BC4</scene>, <scene name='pdbsite=BC5:Man+Binding+Site+For+Residue+E+3284'>BC5</scene>, <scene name='pdbsite=BC6:Nag+Binding+Site+For+Residue+E+3891'>BC6</scene>, <scene name='pdbsite=BC7:Nag+Binding+Site+For+Residue+E+4201'>BC7</scene>, <scene name='pdbsite=BC8:Nag+Binding+Site+For+Residue+I+3281'>BC8</scene>, <scene name='pdbsite=BC9:Nag+Binding+Site+For+Residue+I+3282'>BC9</scene>, <scene name='pdbsite=CC1:Bma+Binding+Site+For+Residue+I+3283'>CC1</scene>, <scene name='pdbsite=CC2:Man+Binding+Site+For+Residue+I+3284'>CC2</scene>, <scene name='pdbsite=CC3:Nag+Binding+Site+For+Residue+I+3891'>CC3</scene>, <scene name='pdbsite=CC4:Nag+Binding+Site+For+Residue+I+3892'>CC4</scene>, <scene name='pdbsite=CC5:Bma+Binding+Site+For+Residue+I+3893'>CC5</scene>, <scene name='pdbsite=CC6:Nag+Binding+Site+For+Residue+I+4201'>CC6</scene>, <scene name='pdbsite=CC7:Nag+Binding+Site+For+Residue+M+3281'>CC7</scene>, <scene name='pdbsite=CC8:Nag+Binding+Site+For+Residue+M+3282'>CC8</scene>, <scene name='pdbsite=CC9:Bma+Binding+Site+For+Residue+M+3283'>CC9</scene>, <scene name='pdbsite=DC1:Man+Binding+Site+For+Residue+M+3284'>DC1</scene>, <scene name='pdbsite=DC2:Nag+Binding+Site+For+Residue+M+3891'>DC2</scene>, <scene name='pdbsite=DC3:Nag+Binding+Site+For+Residue+M+3892'>DC3</scene>, <scene name='pdbsite=DC4:Bma+Binding+Site+For+Residue+M+3893'>DC4</scene>, <scene name='pdbsite=DC5:Nag+Binding+Site+For+Residue+M+4201'>DC5</scene>, <scene name='pdbsite=DC6:Nag+Binding+Site+For+Residue+M+4202'>DC6</scene>, <scene name='pdbsite=DC7:Nag+Binding+Site+For+Residue+P+3281'>DC7</scene>, <scene name='pdbsite=DC8:Nag+Binding+Site+For+Residue+P+3282'>DC8</scene>, <scene name='pdbsite=DC9:Bma+Binding+Site+For+Residue+P+3283'>DC9</scene>, <scene name='pdbsite=EC1:Nag+Binding+Site+For+Residue+P+3371'>EC1</scene>, <scene name='pdbsite=EC2:Nag+Binding+Site+For+Residue+P+3891'>EC2</scene>, <scene name='pdbsite=EC3:Nag+Binding+Site+For+Residue+P+4201'>EC3</scene>, <scene name='pdbsite=EC4:Nag+Binding+Site+For+Residue+S+3281'>EC4</scene>, <scene name='pdbsite=EC5:Nag+Binding+Site+For+Residue+S+3282'>EC5</scene>, <scene name='pdbsite=EC6:Bma+Binding+Site+For+Residue+S+3283'>EC6</scene>, <scene name='pdbsite=EC7:Nag+Binding+Site+For+Residue+S+4201'>EC7</scene>, <scene name='pdbsite=EC8:Nag+Binding+Site+For+Residue+V+3281'>EC8</scene>, <scene name='pdbsite=EC9:Nag+Binding+Site+For+Residue+V+3282'>EC9</scene>, <scene name='pdbsite=FC1:Bma+Binding+Site+For+Residue+V+3283'>FC1</scene>, <scene name='pdbsite=FC2:Nag+Binding+Site+For+Residue+V+3891'>FC2</scene>, <scene name='pdbsite=FC3:Nag+Binding+Site+For+Residue+V+4201'>FC3</scene>, <scene name='pdbsite=FC4:So4+Binding+Site+For+Residue+O+214'>FC4</scene>, <scene name='pdbsite=FC5:So4+Binding+Site+For+Residue+A+1'>FC5</scene>, <scene name='pdbsite=FC6:So4+Binding+Site+For+Residue+G+214'>FC6</scene>, <scene name='pdbsite=FC7:So4+Binding+Site+For+Residue+U+214'>FC7</scene>, <scene name='pdbsite=FC8:So4+Binding+Site+For+Residue+K+214'>FC8</scene>, <scene name='pdbsite=FC9:So4+Binding+Site+For+Residue+E+1'>FC9</scene>, <scene name='pdbsite=GC1:So4+Binding+Site+For+Residue+X+214'>GC1</scene> and <scene name='pdbsite=GC2:So4+Binding+Site+For+Residue+V+1'>GC2</scene> | ||
| + | |LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> and <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] | ||
| + | |GENE= EGFR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), EGFR, ERBB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | }} | ||
| + | |||
| + | '''Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8''' | ||
| + | |||
==About this Structure== | ==About this Structure== | ||
| - | 3B2U is a [ | + | 3B2U is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2U OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: ubl conjugation]] | [[Category: ubl conjugation]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:55:39 2008'' |
Revision as of 16:55, 20 March 2008
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| , resolution 2.580Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , and | ||||||
| Ligands: | and | ||||||
| Gene: | EGFR (Homo sapiens), EGFR, ERBB1 (Homo sapiens) | ||||||
| Activity: | Receptor protein-tyrosine kinase, with EC number 2.7.10.1 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8
About this Structure
3B2U is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:55:39 2008
Categories: Homo sapiens | Protein complex | Receptor protein-tyrosine kinase | Ferguson, K M. | Kussie, P. | Li, S. | NAG | SO4 | Alternative splicing | Anti-oncogene | Atp-binding | Cell cycle | Cell surface receptor; glycoprotein; antigen:antibody complex; fab fragment; antitumor; drug | Disease mutation | Immune system/transferase complex | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Secreted | Transferase | Transmembrane | Tyrosine-protein kinase | Ubl conjugation
