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4ixd

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{{STRUCTURE_4ixd| PDB=4ixd | SCENE= }}
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==X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution==
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===X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution===
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<StructureSection load='4ixd' size='340' side='right' caption='[[4ixd]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ixd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IXD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1HV:4-(3-{4-[(3-AMINOPROPYL)CARBAMOYL]PHENYL}-1H-INDAZOL-1-YL)-N-METHYLBENZAMIDE'>1HV</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xdg|1xdg]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ITGAL, CD11A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ixd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ixd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ixd RCSB], [http://www.ebi.ac.uk/pdbsum/4ixd PDBsum]</span></td></tr>
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</table>
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==Function==
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==See Also==
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[[http://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN]] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
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*[[Integrin|Integrin]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4ixd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IXD OCA].
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[[Category: Human]]
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[[Category: Kallen, J.]]
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[[Category: Kallen, J]]
[[Category: I-domain]]
[[Category: I-domain]]
[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Rossman-fold]]
[[Category: Rossman-fold]]

Revision as of 18:44, 21 December 2014

X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution

4ixd, resolution 1.80Å

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