4lxj
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4lxj| PDB=4lxj | SCENE= }} | {{STRUCTURE_4lxj| PDB=4lxj | SCENE= }} | ||
===Saccharomyces cerevisiae lanosterol 14-alpha demethylase with lanosterol bound=== | ===Saccharomyces cerevisiae lanosterol 14-alpha demethylase with lanosterol bound=== | ||
| + | {{ABSTRACT_PUBMED_24613931}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4lxj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LXJ OCA]. | [[4lxj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LXJ OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:024613931</ref><references group="xtra"/><references/> | ||
[[Category: Sterol 14-demethylase]] | [[Category: Sterol 14-demethylase]] | ||
[[Category: Cannon, R D.]] | [[Category: Cannon, R D.]] | ||
Revision as of 06:27, 26 March 2014
Contents |
Saccharomyces cerevisiae lanosterol 14-alpha demethylase with lanosterol bound
Template:ABSTRACT PUBMED 24613931
Function
[CP51_YEAST] Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
About this Structure
4lxj is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Monk BC, Tomasiak TM, Keniya MV, Huschmann FU, Tyndall JD, O'Connell JD 3rd, Cannon RD, McDonald JG, Rodriguez A, Finer-Moore JS, Stroud RM. Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3865-70. doi:, 10.1073/pnas.1324245111. Epub 2014 Feb 3. PMID:24613931 doi:http://dx.doi.org/10.1073/pnas.1324245111
