3bbt
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
- | [[Image:3bbt.jpg|left|200px]] | + | [[Image:3bbt.jpg|left|200px]] |
- | + | ||
- | '''crystal structure of the ErbB4 kinase in complex with lapatinib''' | + | {{Structure |
+ | |PDB= 3bbt |SIZE=350|CAPTION= <scene name='initialview01'>3bbt</scene>, resolution 2.800Å | ||
+ | |SITE= <scene name='pdbsite=AC1:Fmm+Binding+Site+For+Residue+B+91'>AC1</scene> and <scene name='pdbsite=AC2:Fmm+Binding+Site+For+Residue+D+91'>AC2</scene> | ||
+ | |LIGAND= <scene name='pdbligand=FMM:N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE'>FMM</scene> | ||
+ | |ACTIVITY= [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] | ||
+ | |GENE= ERBB4, HER4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
+ | }} | ||
+ | |||
+ | '''crystal structure of the ErbB4 kinase in complex with lapatinib''' | ||
+ | |||
==About this Structure== | ==About this Structure== | ||
- | 3BBT is a [ | + | 3BBT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BBT OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
Line 22: | Line 31: | ||
[[Category: tyrosine-protein kinase]] | [[Category: tyrosine-protein kinase]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:57:43 2008'' |
Revision as of 16:57, 20 March 2008
| |||||||
, resolution 2.800Å | |||||||
---|---|---|---|---|---|---|---|
Sites: | and | ||||||
Ligands: | |||||||
Gene: | ERBB4, HER4 (Homo sapiens) | ||||||
Activity: | Receptor protein-tyrosine kinase, with EC number 2.7.10.1 | ||||||
Coordinates: | save as pdb, mmCIF, xml |
crystal structure of the ErbB4 kinase in complex with lapatinib
About this Structure
3BBT is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:57:43 2008