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4nlh

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'''Unreleased structure'''
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==SKICH domain of human TAX1BP1==
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<StructureSection load='4nlh' size='340' side='right' caption='[[4nlh]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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The entry 4nlh is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4nlh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NLH FirstGlance]. <br>
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Authors: Yang, Y., Wang, G., Huang, X., Zhu, J., Du, Z.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nlh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nlh RCSB], [http://www.ebi.ac.uk/pdbsum/4nlh PDBsum]</span></td></tr>
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</table>
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Description: SKICH domain of human TAX1BP1
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== Function ==
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[[http://www.uniprot.org/uniprot/TAXB1_HUMAN TAXB1_HUMAN]] Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.<ref>PMID:10435631</ref> <ref>PMID:10920205</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Du, Z]]
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[[Category: Huang, X]]
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[[Category: Wang, G]]
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[[Category: Yang, Y]]
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[[Category: Zhu, J]]
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[[Category: Ig like fold]]
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[[Category: Protein binding]]

Revision as of 11:06, 24 December 2014

SKICH domain of human TAX1BP1

4nlh, resolution 1.90Å

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