3biy

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[[Image:3biy.jpg|left|200px]]<br /><applet load="3biy" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:3biy.jpg|left|200px]]
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caption="3biy, resolution 1.70&Aring;" />
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'''Crystal structure of p300 histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA'''<br />
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{{Structure
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|PDB= 3biy |SIZE=350|CAPTION= <scene name='initialview01'>3biy</scene>, resolution 1.70&Aring;
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|SITE= <scene name='pdbsite=AC1:Br+Binding+Site+For+Residue+A+1521'>AC1</scene>, <scene name='pdbsite=AC2:Br+Binding+Site+For+Residue+A+1525'>AC2</scene> and <scene name='pdbsite=AC3:01k+Binding+Site+For+Residue+A+700'>AC3</scene>
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|LIGAND= <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene> and <scene name='pdbligand=01K:'>01K</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48]
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|GENE= EP300, P300 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal structure of p300 histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA'''
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==About this Structure==
==About this Structure==
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3BIY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=BR:'>BR</scene> and <scene name='pdbligand=01K:'>01K</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] Known structural/functional Sites: <scene name='pdbsite=AC1:Br+Binding+Site+For+Residue+A+1521'>AC1</scene>, <scene name='pdbsite=AC2:Br+Binding+Site+For+Residue+A+1525'>AC2</scene> and <scene name='pdbsite=AC3:01k+Binding+Site+For+Residue+A+700'>AC3</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BIY OCA].
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3BIY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BIY OCA].
[[Category: Histone acetyltransferase]]
[[Category: Histone acetyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: bisubstrate inhibitor]]
[[Category: bisubstrate inhibitor]]
[[Category: p300 hat]]
[[Category: p300 hat]]
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[[Category: protein-inhibitor complex ]]
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[[Category: protein-inhibitor complex]]
[[Category: transferase]]
[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:06:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:59:27 2008''

Revision as of 16:59, 20 March 2008


PDB ID 3biy

Drag the structure with the mouse to rotate
, resolution 1.70Å
Sites: , and
Ligands: and
Gene: EP300, P300 (Homo sapiens)
Activity: Histone acetyltransferase, with EC number 2.3.1.48
Coordinates: save as pdb, mmCIF, xml



Crystal structure of p300 histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA


About this Structure

3BIY is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 18:59:27 2008

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